Results 71 to 80 of about 349,476 (296)

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

open access: yesAdvanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng   +8 more
wiley   +1 more source

5,6,7,8-tetrahydroneopterin (NH4) Acts like an Endogenous Superoxide Dismutase

open access: yesPteridines, 1996
The protective effect of 5,6,7,8-tetrahydroneopterin (NH.) against radiation injury in mice was studied. (C57BL/6x A/J)F1 mice received whole body irradiation with a single fatal dose of 8.0 Gy X-ray.
Sawada Suguru   +5 more
doaj   +1 more source

Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria

open access: yesBioengineering, 2017
Interactions of nanoparticles with biological matter—both somatically and in nature—draw scientists’ attention. Nanoparticulate systems are believed to be our saviors, acting as versatile drug delivery vehicles.
Dmitry Gil   +5 more
doaj   +1 more source

Superoxide dismutase triggers activation of primed platelets

open access: yes, 1991
Superoxide dismutase (SOD) triggers activation of human platelets exposed to subthreshold concentrations of arachidonic acid and collagen. The subthreshold concentrations used are not able to activate platelets but "prime" platelets to be activated by ...
PRATICÒ D   +4 more
core   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen   +11 more
wiley   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

open access: yesAdvanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie   +7 more
wiley   +1 more source

Studies on superoxide dismutase inhibition and application of methods to study metal ion participation in complication of diabetes [PDF]

open access: yes, 2012
Studies on Superoxide Dismutase Inhibition We used NMR relaxation rates to study reactions of the enzyme superoxide dismutase (SOD) with low molecular weight polyphenolic compounds. While the compounds appeared to inhibit SOD, we discovered evidence that
NC DOCKS at Western Carolina University   +1 more
core  

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li   +9 more
wiley   +1 more source

A New Method for the Purification of Cu-Zn Superoxide Dismutase from Human Erythrocytes [PDF]

open access: yesIranian Journal of Public Health, 2005
The human erythrocyte is a rich raw material for the purification of Cu-Zn superoxide dismutase (SOD). We applied a simple and rapid procedure for the purification of SOD from human erythrocytes by ion exchange chromatography.
M Djalali   +6 more
doaj   +2 more sources

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