Results 151 to 160 of about 248,641 (339)

Superoxide dismutase kinetics

, 2002
FALCONI, MATTIA, O'Neill, P, Stroppolo, ME, DESIDERI, ALESSANDRO   +3 more
openaire   +3 more sources

Superoxide [PDF]

, 2020
openaire   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Enthalpic Barriers Dominate the Folding and Unfolding of the Human Cu, Zn Superoxide Dismutase Monomer

, 2012
Can Kayatekin, Noah R. Cohen, C. Robert Matthews   +2 more
openalex   +2 more sources

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

Perfluorochemical Liquids Enhance Delivery of Superoxide Dismutase to the Lungs of Juvenile Rabbits [PDF]

, 2006
Luca Brunelli, E. Hamilton, Jonathan M. Davis, Hshi-Chi Koo, Ansamma Joseph, Jeffrey A. Kazzaz, Marla R. Wolfson, Thomas H. Shaffer   +7 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Nanoformulated copper/zinc superoxide dismutase reduces adipose inflammation in obesity [PDF]

, 2015
Curtis Perriotte‐Olson, Nikhil Adi, Devika S. Manickam, Rachel A. Westwood, Cyrus Desouza, Kavumpurathu Raman Thankappan, Alexandra A. Crook, Alexander V. Kabanov, Viswanathan Saraswathi   +8 more
openalex   +1 more source

Visible Light‐Activated ZnO@CuO Coaxial Nanofibers Enhance Infected Skin Wound Healing Through Construction of p‐n Heterojunctions

Advanced Science, EarlyView.
Coaxial ZnO@CuO nanofibers activated by visible light generate ROS through enhanced photocatalytic reactions driven by improved electron hole separation in the heterojunction. This strategy enables rapid antimicrobial activity and early infection control, thereby promoting the healing of MRSA infected and diabetic wounds with biosafe and easily ...
Pengrui Dang, Han Zhao, Chenguang Zhang, Jiechen Wang, Fangyu Zhu, Qinqiu Zhong, Wenyi Zeng, Xinyuan Wang, Yumin Chen, Xu Yan, Xuliang Deng, Wenwen Liu   +11 more
wiley   +1 more source

Concentration-dependent effects of bacterial melanin on new superoxide-producing associates in rat tissues: a rotenone neurotoxic model of parkinson's disease. [PDF]

BMC Pharmacol Toxicol
Danielyan M, Karapetyan K, Simonyan R, Simonyan G, Babayan M, Poghosyan M, Yekmalyan H, Simonyan M, Simonyan K, Nebogova K.   +9 more
europepmc   +1 more source