Results 161 to 170 of about 248,641 (339)

Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic [PDF]

, 2020
Benjamin G. Trist, James B. Hilton, Dominic J. Hare, Peter J. Crouch, Kay L. Double   +4 more
openalex   +1 more source

Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling

Oncogene, 2006
Yongmin Liu, G. Borchert, A. Surażyński, Chien-An A. Hu, J. Phang   +4 more
semanticscholar   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

THE ACTIVITY OF SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE IN KIDNEYS AND LIVER OF MICE EXPOSED TO ACRYLAMIDE

, 2021
Kinga Kraska, Grzegorz Formicki, Marta Kopańska, Edyta Kapusta   +3 more
openalex   +1 more source

Effect of ingested pentoxifylline on neutrophil superoxide anion production [PDF]

, 1992
S P Crouch, John Fletcher
openalex   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

A roadmap to chemically reactive species: how diverse oxidants affect <i>Candida albican</i><i>s</i> and other fungi. [PDF]

Microbiol Mol Biol Rev
Swenson KA, Alberti L, Teele K, Yadav A, Shah SJ, Konopka JB.   +5 more
europepmc   +1 more source

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source

From Lithium and Sodium Superoxides to Singlet-Oxygen - Insights into the Mechanism of Dissociation Using SHARC-MD. [PDF]

Chemphyschem
Pietruschka DS, Zaichenko A, Richter M, Gräfe S, Mollenhauer D.   +4 more
europepmc   +1 more source

Nickel amine/imine and amine/amide bisthiolate complexes as models for the active site of nickel superoxide dismutase

, 2018
Nilmini K. Senaratne
openalex   +1 more source