SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai +15 more
wiley +1 more source
The PI3K Inhibitor HCD Promotes Caspase Activation in Head and Neck Squamous Cells by Upregulating the Extrinsic and Intrinsic Apoptosis Pathways. [PDF]
Chan LP +9 more
europepmc +1 more source
A defect‐engineered pyrene‐based covalent organic framework (TP‐PYTO‐SA) is developed via strategic salicylaldehyde incorporation. This approach simultaneously enhances hydrophilicity and introduces uranyl coordination sites, while optimized defect density significantly improves charge separation.
Weikun Yao +5 more
wiley +1 more source
Bimetallic Cu/Zn Single-Atom Nanozyme with Superoxide Dismutase-Like Activity. [PDF]
Hamed EM, Fung FM, Li SFY.
europepmc +1 more source
Chemical Upcycling of Polyphenylene Sulfide at Room Temperature
Poly(phenylene sulfide) (PPS) is a semi‐crystalline super engineering plastic with exceptional properties. An iron‐photocatalyzed strategy is reported for chemical upcycling of PPS plastics at room temperature using 1,2‐dichloroethane. The method demonstrates remarkable efficiency across diverse PPS resins and post‐consumer composites, even within ...
Boning Gu, Chengliang Li, Xuefeng Jiang
wiley +1 more source
Superoxide Scavenging by Capers and Kaempferol, Measured by Hydrodynamic Voltammetry, Shows Kaempferol Synergistic Action with Vitamin C; Density Functional Theory (DFT) Results Support Experimental Kaempferol Catalytic Behavior Similar to Superoxide Dismutases (SODs). [PDF]
Rossi M +6 more
europepmc +1 more source
Lithium–oxygen batteries face an energy‐power trade‐off due to sluggish O2 transport and pore clogging by Li2O2. Simulations show that reducing tortuosity via interconnected macropores enhances oxygen mobility. A freestanding graphene electrode having interconnected macropores with low tortuosity delivers >2500 mAh g−1, stable lean‐electrolyte cycling,
Arghya Dutta +7 more
wiley +1 more source
MnTBAP, a peroxynitrite scavenger, attenuates cisplatin-induced apoptosis and cytotoxicity in organ of Corti cells. [PDF]
Shahab M +4 more
europepmc +1 more source
Nanozymes Integrated Biochips Toward Smart Detection System
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen +10 more
wiley +1 more source

