Results 71 to 80 of about 145 (85)

Molecular mechanism of sulfide and supersulfide sensing

生化学, 2021
Shimizu, Takayuki, Masuda, Shinji
openaire   +1 more source

Dynamic Transformation of the Sulfur Metabolome during Natto Fermentation: Supersulfide Omics Study

Nitric Oxide
Supersulfides are sulfur species with catenated sulfur atoms, such as cysteine hydropersulfide (CysSSH). Although supersulfides are biologically important metabolites owing to their unique chemical properties, their transformation in plants via microbial fermentation remains unknown. Natto is a traditional Japanese food prepared from soybeans fermented
Tomoaki Ida, Shingo Kasamatsu, Mahiro Kuryu, Haruka Nitta, Wakana Nagamura, Hina Yoshida, Ayaka Kinno, Aoi Morishita, Takaaki Akaike, Hideshi Ihara   +9 more
openaire   +2 more sources

Development of a genetically encoded supersulfide-dependent translocation reporter

Abstract Supersulfides are emerging sulfur-containing signaling molecules involved in redox regulation, mitochondrial function, and protein S-sulfhydration. However, their dynamic behavior in living mammalian systems remains poorly understood because existing analytical methods require destructive sample preparation or lack sufficient ...
Shouhei Misaki, Tatsuya Kandaka, Takashi Tanida, Shingo Kasamatsu, Tomoya Ito, Hideshi Ihara, Yasu-Taka Azuma, Motohiro Nishida, Kazuhiro Nishiyama   +8 more
openaire   +1 more source

Unveiling the role of supersulfides in cancer progression: From malignancy to therapeutic horizons

Ferroptosis and Oxidative Stress
Sulfur, like oxygen, belongs to group 16 of the periodic table and exhibits remarkable versatility in both electron donation and acceptance, as well as in its wide range of oxidation states. These properties enable sulfur to participate in diverse redox reactions, while also serving as a critical component of enzyme active sites and redox sensors ...
Hozumi Motohashi
exaly   +2 more sources

Supersulfide metabolome of exhaled breath condensate for diagnostic biomarkers of esophageal cancer.

Journal of Clinical Oncology
e15027 Background: The early estimate and detection of esophageal cancer (EC) is essentially required for continuous esophagogastroduodenoscopy and histopathological diagnosis. However, endoscopic examination is sometimes invasive, which may cause somehow limited clinical application and compliance.
Seji Asamitsu, Yohei Ozawa, Seiryo Ogata, Hiroshi Okamoto, Jun Yoshitake, Tetsuro Matsunaga, Yusuke Taniyama, Chiaki Sato, Hirotaka Ishida, Takaaki Abe, Takaaki Akaike, Takashi Kamei   +11 more
openaire   +1 more source

Gut Microbial Supersulfides Create a Reducing Microenvironment and Regulate Protein Supersulfidation

Free Radical Biology and Medicine
Jun Uchiyama, Masahiro Akiyama
openaire   +1 more source

Supersulfide-Mediated Signaling during Differentiation and De-Differentiation

2021
Tsuyoshi Takata, Masanobu Morita, Tetsuro Matsunaga, Hozumi Motohashi, Takaaki Akaike   +4 more
openaire   +1 more source

Supersulfide metabolism in cardiac stress resistance

Free Radical Biology and Medicine
Motohiro Nishida, Akiyuki Nishimura
openaire   +1 more source

Supersulfide Synthesis in Mitochondria is Essential for Mitochondrially-Encoded Protein Expression

Free Radical Biology and Medicine
Shohei Murakami, Ryutaro Komori, Masanobu Morita, Tomoaki Ida, Takaaki Akaike, Hozumi Motohashi   +5 more
openaire   +1 more source

Functional roles of mitochondrial supersulfide production

Free Radical Biology and Medicine
openaire   +1 more source