Results 91 to 100 of about 307,863 (250)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
spa: Semi-Supervised Semi-Parametric Graph-Based Estimation in R [PDF]
In this paper, we present an R package that combines feature-based (X) data and graph-based (G) data for prediction of the response Y . In this particular case, Y is observed for a subset of the observations (labeled) and missing for the remainder ...
Mark Culp
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
newalexander/supervised-cadres: Supervised cadre models via TensorFlow
, 2019 <p>Implementation of supervised cadre models in TensorFlow. Support for regression and classification models.
Alexander New
core +1 more source
Supervised Saliency Mapping for First-Person Videos With an Inverse Sparse Coding Framework
IEEE Access, 2019 Saliency mapping is an efficient means of processing large amounts of incoming visual information from images and videos. Existing methods based on feature integration and construction error provide a rough saliency mapping and are sensitive to real ...
Yujie Li +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Supervised and Unsupervised Learning Technology in the Study of Rodent Behavior
Frontiers in Behavioral Neuroscience, 2017 Quantifying behavior is a challenge for scientists studying neuroscience, ethology, psychology, pathology, etc. Until now, behavior was mostly considered as qualitative descriptions of postures or labor intensive counting of bouts of individual movements.
Katsiaryna V. Gris +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Predictive Modeling of the Hydrate Formation Temperature in Highly Pressurized Natural Gas Pipelines
EnergiesIn this study, we aim to develop advanced machine learning regression models for the prediction of hydrate temperature based on the chemical composition of sweet gas mixtures.
Mustafa Karaköse, Özgün Yücel
doaj +1 more source