Results 131 to 140 of about 889,365 (318)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Application of a Multispectral SPOT Image for Land Use Classification in Sampean Watershed

Journal of Tropical Soils, 2011
This article described the process of land use classification at Sampean Watershed. The research was conducted in Sampean watershed to calculate the land use area using a multispectral SPOT image.
Januar Fery Irawan, Indarto
doaj  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Semi-supervised latent variable models for sentence-level sentiment analysis [PDF]

, 2011
We derive two variants of a semi-supervised model for fine-grained sentiment analysis. Both models leverage abundant natural supervision in the form of review ratings, as well as a small amount of manually crafted sentence labels, to learn sentence-level
McDonald, Ryan, Täckström, Oscar
core  

Convex Multiview Semi-Supervised Classification

, 2017
In many practical applications, there are a great number of unlabeled samples available, while labeling them is a costly and tedious process. Therefore, how to utilize unlabeled samples to assist digging out potential information about the problem is ...
Feiping Nie, Jing Li, Nie, Feiping, Li, Xuelong, Li, Jing, Xuelong Li   +5 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Automatic transcription of multi-genre media archives

, 2013
This paper describes some recent results of our collaborative work on developing a speech recognition system for the automatic transcription or media archives from the British Broadcasting Corporation (BBC).
Liu, X, Woodland, Phil, Renals, S., Gales, M.J.F., Long, Y, Liu, X., Saz, O., Seigel, M.S., Swietojanski, Pawel, Quinnell, J., Bell, P.J., Swietojanski, P., Quinnell, Jennifer, Saz, Oscar, Liu, Xunying, Long, Yanhua, Quinnell, J, Gales, Mark, Hain, T, Bell, Peter, Bell, PJ, Long, Y., Lanchantin, P., Hain, T., Gales, MJF, ,, Renals, S, Renals, Steve, Seigel, Matt, Hain, Thomas, Lanchantin, P, Woodland, P.C., Swietojanski, P, Lanchantin, Pierre, Seigel, MS, Woodland, PC, Saz, O   +36 more
core  

Supervision Quartets [PDF]

Postgraduate Medical Journal, 2012
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source