Results 71 to 80 of about 9,445,647 (302)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Market newsletter 2/2023 [PDF]

open access: yes, 2023
In its supervision, the Financial Supervisory Authority (FIN-FSA) has paid attention to communication between issuers and ...

core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Compositional supervisory control via reactive synthesis and automated planning [PDF]

open access: yes, 2019
We show how reactive synthesis and automatedplanning can be leveraged effectively to find non-maximal solu-tions to deterministic supervisory control problems of discreteevent systems.
Ciolek, Daniel   +4 more
core   +1 more source

Supervisory control theory with Alloy

open access: yesScience of Computer Programming, 2014
Scientific literature reveals that the symbolic representation techniques underlying some formal methods are useful in verifying properties or synthesizing parts of large discrete event systems. They involve, however, encoding complex schemata and fine-tuning heuristic parameters in order to translate specific problems into efficient BDD- or SAT-based ...
Benoît Fraikin   +2 more
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Supervisory control on concurrent discrete event systems with variables

open access: yes, 2022
S.4274-4279This work deals with the supervisory control of Discrete Event Systems (DES). Supervisory control is classically applied to systems modeled by Finite State Machine (FSM).
Deussen, P.H., Gaudin, B.
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Analysis and Control of Partially Observed Discrete-Event Systems via Positively Constructed Formulas

open access: yesComputation
This paper establishes a connection between control theory for partially observed discrete-event systems (DESs) and automated theorem proving (ATP) in the calculus of positively constructed formulas (PCFs).
Artem Davydov   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy