Results 91 to 100 of about 41,229 (313)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Modular control-loop detection [PDF]
, 2006 This paper presents an efficient algorithm to detect control-loops in large finite-state systems. The proposed algorithm exploits the modular structure present in many models of practical relevance, and often successfully avoids the explicit ...
Malik, Robi, Malik, Petra
core +1 more source
Quantifying model quality for supervisory control synthesis - an experimental study [PDF]
, 2020 Supervisory control synthesis is a model-based engineering method to design supervisory controllers for high-tech and cyber-physical systems. Recent advances in synthesis techniques and modelling formalisms allow for synthesis of supervisors for large ...
Goorden, Martijn A.; id_orcid +4 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Theory of Regions for Control Synthesis without Computing Reachability Graph
Applied Sciences, 2017 This paper addresses the design of Petri net (PN) supervisor using the theory of regions for forbidden state problem with a set of general mutual exclusion constraints. In fact, as any method of supervisory control based on reachability graph, the theory
Sadok Rezig, Zied Achour, Nidhal Rezg
doaj +1 more source
Probabilistic Supervisory Control of Probabilistic Discrete Event Systems [PDF]
, 2011 This thesis considers probabilistic supervisory control of probabilistic discrete event systems (PDES). PDES are modeled as generators of probabilistic languages.
Pantelic, Vera
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source