Results 301 to 310 of about 2,455,219 (389)

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Maternal Protein Restriction and Branched-Chain Amino Acid Supplementation Differentially Affect Maternal Energy Balance and Impair Offspring Growth. [PDF]

Nutrients
Redrovan D, Patra S, Aziz MT, Gorton MW, Chavez EA, Frederiksen S, Rowe J, Pezeshki A, Chelikani PK.   +8 more
europepmc   +1 more source

Supplemental folic acid in pregnancy and maternal cancer risk

, 2015
Jan Helge Seglem Mortensen, Nina Øyen, Tatiana Fomina, Mads Melbye, Steinar Tretli, Dan J. Stein, Tone Bjørge   +6 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Effects of vitamin A and vitamin D₃ supplementation on child growth and development in low- and middle-income countries: a systematic review and meta-analysis. [PDF]

Transl Pediatr
Peng L, Zhao J, Duan C, Yan J, Li D, Yang Y, He D.   +6 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Efficacy of Supplementary Guanidinoacetic Acid at Different Dietary Crude Protein Levels on the Productive Performance, Egg Quality, Intestinal Morphology, Antioxidative Status, and Serum Metabolites of Aged Laying Hens Exposed to High Ambient Temperatures. [PDF]

Vet Med Sci
Mahdavi R, Piray AH, Ghazi S, Nooriyan Soroor ME, Malorodov VV.   +4 more
europepmc   +1 more source