Results 331 to 340 of about 2,455,219 (389)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Effect of supplementation of phytase and its combination with xylanase, amylase, and protease on growth performance, carcass quality and nutrient utilization of yellow-feathered broilers fed diets with lower nutritional density. [PDF]

Poult Sci
He X, Wang X, Wu J, Zhang X, Ghane AE, Wei S, Zhang H, Fan Y, Ye H, Zhu Y.   +9 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Choline supplementation in preterm infants: effects of four different supplements on choline plasma concentrations. [PDF]

Eur J Nutr
Böckmann KA, Bernhard W, Minarski M, Shunova A, Schwarz J, Poets CF, Franz AR.   +6 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Randomized, placebo-controlled trial reveals the impact of dose and timing of <i>Bifidobacterium infantis</i> probiotic supplementation on breastfed infants' gut microbiome. [PDF]

mSphere
O'Brien CE, Frese SA, Cernioglo K, Damian-Medina K, Mitchell RD, Casaburi G, Melnyk RA, Henrick BM, Smilowitz JT.   +8 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Assessing the potency of vitamin D augmentation on saccharometric indices in type 2 diabetes: a meta-analysis. [PDF]

Front Nutr
Gong S, Chen L.
europepmc   +1 more source

Rutin Improved the Meat Quality and Hepatointestinal Health of Nile Tilapia (<i>Oreochromis niloticus</i>) After High-Level Fava Bean Feeding. [PDF]

Aquac Nutr
Cheng K, Zhang X, Dong L, Peng D, Liu Y, Zhu D, Guo Z, Luo Y, Liu A, Tian J, Wen H, Liu M, Jiang M.   +12 more
europepmc   +1 more source

Influence of substituting 25% alfalfa hay with Panicum maximum cv. Mombasa with or without spirulina supplementation on the productive performance of fattening Barki lambs. [PDF]

Sci Rep
Meteab MI, Khorshed MM, El-Essawy AM, Nassar MS, El-Bordeny NES.   +4 more
europepmc   +1 more source