Results 81 to 90 of about 506,885 (307)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Introduction to the supplement [PDF]
The concepts of child and adolescent psychiatric disorders show both continuity and change. Whereas the main broad psychopathological phenomena do not change fundamentally, there is an ongoing process of refining diagnostic criteria of various disorders, delineating new subtypes, and, from time to time, also the definition of a new diagnostic entity ...
openaire +4 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
São Paulo State Univ, São Paulo, BrazilBellman Anim Nutr Mineral Supplements, São Paulo, BrazilSão Paulo State Univ, São Paulo ...
Pereira, G. T. [UNESP] +4 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Use of sport supplements and doping substances by athletes: Prevalence and relationships [PDF]
Background: The use of sport supplements may represent a risk factor for the use of doping in sports. To explore this putative risk, the current study examined the frequency of sport supplement use and associations between the use of sport supplements ...
Kavussanu, M. +4 more
core +1 more source
Micronutrient supplements for children after deworming [PDF]
The availability of a few inexpensive, single dose drugs to treat soil-transmitted helminths and schistosomiasis offers the potential to reduce a considerable burden of acute disease, especially among children sub-Saharan Africa.
Hall, A.
core +1 more source
Serum-free media supplements carry miRNAs that co-purify with extracellular vesicles
Recent studies on extracellular RNA raised awareness that extracellular vesicles (EVs) isolated from cultured cells may co-purify RNAs derived from media supplements such as fetal bovine serum (FBS) confounding EV-associated RNA.
Martin Auber +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Supp 1: List of 87 cities examined Supp 2: Database of all information extracted from programs Supp 3: Metadata which describes each column in Supp ...
Nina Fogel (14726941)
core +1 more source

