Results 91 to 100 of about 1,687,730 (310)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

SUPPLY CHAIN DIGITALIZATION, GREEN SUPPLY CHAIN, SUPPLY CHAIN RESILIENCE TOWARD COMPETITIVENESS AND MSMES PERFORMANCE

open access: yesJurnal Aplikasi Manajemen
MSMEs that previously only relied on human resources are now forced to keep up with the times by utilizing IT in every process, from raw material procurement, production processes to distribution processes in order to remain competitive in facing a business world full of challenges.
Zainurrafiqi Zainurrafiqi, Gazali Gazali
openaire   +2 more sources

Cluster Development and Knowledge Exchange in Supply Chain

open access: yes, 2008
Industry cluster and supply chain are in focus of every countries which rely on knowledge-based economy. Both focus on improving the competitiveness of firm in the industry in the different aspect.
Bouras, Abdelaziz   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A comparative analysis of last mile delivery in Kenya’s online retail subsector [PDF]

open access: yesThe Retail and Marketing Review
Success in online retailing depends on effective and efficient last mile delivery. Although online retailing in Kenya has considerable potential to ensure sustainable trade and economic growth, progress in this subsector has been inhibited by several ...
Eric Mogire, Peter Kilbourn, Rose Luke
doaj   +1 more source

FedEx Case Study: Links in the Chain [PDF]

open access: yes
Supply chain management improves competition by controlling costs and shortening product delivery cycles.supply chain, global supply chain, FedEx, supply chain management, Tennessee ...
Scott Gardner
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Critical Management Issues for Implementing RFID in Supply Chain Management [PDF]

open access: yes, 2010
The benefits of radio frequency identification (RFID) technology in the supply chain are fairly compelling. It has the potential to revolutionise the efficiency, accuracy and security of the supply chain with significant impact on overall profitability ...
Srivastava, Bharatendu
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Study on Early Warning Methods for Shipping Input Risks Under Consideration of Public Health Events

open access: yesApplied Sciences
The rapid expansion of economic globalization and trade has led to a sharp increase in the shipping investment risks currently faced by cities around the world.
Zhanxin Ma   +3 more
doaj   +1 more source

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