Results 91 to 100 of about 515,827 (317)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Systemic Risk and the Ripple Effect in the Supply Chain
, 2019 Supply chains are highly complex systems, and disruptions may ripple through these systems in unexpected ways, but they may also start in unexpected ways. We investigate the causes of ripple effect through the lens of systemic risk.
Jennifer Blackhurst +3 more
core +1 more source
Taxonomy of digital signage message execution and media placement considerations [PDF]
The Retail and Marketing Review, 2020 Digital signage is a commercial promising field in marketing. Yet, it is a little researched topic, with an incomplete understanding of the factors to consider when planning digital signage message executions or media placements.
E M Xaba, AT Roux, GAP Drotsky
doaj
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Peace, Cocaine, and Supply Chain Resiliency
, 2021 Every industry has a supply chain as its backbone. When disruptions to the supply chain occur, a company must work quickly to adapt. It was found that more peaceful countries have a higher supply chain resiliency, but does this theory apply to every ...
Peterson, Abigail
core
Scientific ReportsThe progress of the transmission remanufacturing industry is in line with the development requirements of the circular economy, but its environmental pollution problems are easily ignored.
Zhuowen Wang +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Trade Facilitation and Supply Chain Network Design
, 2011 World trade has expanded rapidly over the past decades. Low production costs in developing countries,along with cost efficient logistics networks have led to the allocation of manufacturing plants in offshoreindustrial sites.
Iakovou, Eleftherios +3 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source