Results 71 to 80 of about 515,827 (317)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Digital BusinessThe purpose of this paper is to contribute to the existing body of research on digital platforms by adopting an ecosystem perspective and considering an established framework. Through our work, we synthesize previous findings related to digital platforms
Thomas Goertler +3 more
doaj +1 more source
IEEE Internet Computing, 2001 A recent study found that supply-chain problems cost companies between 9 and 20 percent of their value over a six-month period (T.J. Becker, 2000). The problems range from part shortages to poorly utilized plant capacity. When you place this in the context of the overall business-to-business (B2B) market expected to reach US$7 trillion by 2004 (37 ...
Huhns, Michael N., Stevens, Larry M.
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Demand chain management-integrating marketing and supply chain management [PDF]
, 2007 This paper endorses demand chain management as a new business model aimed at creating value in today's marketplace, and combining the strengths of marketing and supply chain competencies.
Christopher, Martin +2 more
core +1 more source
, 2023 This book provides insights from research and practice in how organizations were able to sustain resilience in their global supply chains during the COVID-19 pandemic and to advance the understanding of supply chain risk management.
core +1 more source
RecyclingThe rising amount of electronic waste (e-waste) presents serious threats to the environment and public health. Addressing this challenge necessitates a focus on improving the e-waste recycling rate, which is facilitated by consumers’ spontaneous ...
Md Hasibul Islam +6 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Acta Commercii, 2017 Objective: The objective was to analyse the integration of and collaboration between strategic sourcing and supplier development at Eskom, South Africa’s primary electricity supplier, and to determine how strategic sourcing can be a catalyst for supplier
Mzoxolo E. Mbiko +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source