Results 71 to 80 of about 1,687,730 (310)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Forecast accuracy in demand planning: A fast-moving consumer goods case study

Journal of Transport and Supply Chain Management, 2019
Background: An established South African fast-moving consumer goods (FMCG) manufacturer, Company A, sought to address an underperforming supply chain through an attempt to improve demand planning accuracy.
Lisa M. Basson, Peter J. Kilbourn, Jackie Walters   +2 more
doaj   +1 more source

Dancing the Supply Chain: Toward Transformative Supply Chain Management [PDF]

Journal of Supply Chain Management, 2020
Most of the theories that have dominated supply chain management (SCM) take a reductionist and static view on the supply chain and its management, promoting a global hunt for cheap labor and resources. As a result, supply chains tend to be operated without much concern for their broader contextual environment.
openaire   +2 more sources

A General Simulation Framework for Supply Chain Modeling: State of the Art and Case Study

, 2010
Nowadays there is a large availability of discrete event simulation software that can be easily used in different domains: from industry to supply chain, from healthcare to business management, from training to complex systems design.
Cimino, Antonio, Longo, Francesco, Mirabelli, Giovanni   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Australian Lamb Supply Chain: A Conceptual Framework [PDF]

In the last decade, supply chain management has played an important role to lead agribusiness today to succeed in their business goals, to gain competitive advantages, and to improve business performance.
Jie, Ferry
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The structure of cross-ventilation flow in an isolated cylindrical building: Numerical study

Energy and Built Environment
Cross-ventilation serves as an efficient means to expel pollutants and heat from buildings, requiring no energy consumption due to variations in wind pressure. The structure of the cross-ventilation flow significantly influences ventilation effectiveness.
Puxian Ding, Di Fan, Ye Feng, Shiming Liu, Xiaoqing Zhou   +4 more
doaj   +1 more source

Agency Theory and Supply Chain Management: Goals and Incentives in Supply Chain Organisations [PDF]

, 2007
Purpose Agency theory (AT) offers opportunities to examine how the risk of opportunism can be prevented or minimised along supply chain organisations using incentives to achieve goal alignment. Methodology The study presents evidence of how members of
Hornibrook, Susan A.
core  

An exploratory treatise on consciousness and espousal of halal supply-chain: an Indian perspective [PDF]

, 2017
The purpose of this research is to be acquainted with the awareness and approval of halal supply chain among Indian manufacturers and distribution network members for haulage and warehousing activities from the perception of respective service suppliers.
Lee, Jung Wan, Potluri, Lohith Sekhar, Potluri, Rajasekhara Mouly   +2 more
core   +1 more source