Results 61 to 70 of about 3,810,215 (317)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
EntropySteam turbine blades may crack, break, or suffer other failures due to high temperatures, high pressures, and high-speed rotation, which seriously threatens the safety and reliability of the equipment.
Qinglei Zhang +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Investigating stock-outs in Johannesburg’s warehouse retail liquor sector
Journal of Transport and Supply Chain Management, 2017 Purpose: The aim of this exploratory study was to investigate how management practices and processes contribute to stock-outs in the warehouse retail liquor sector in Johannesburg.
Amit Govind, Rose Luke, Noleen Pisa
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Journal of Electrical and Computer EngineeringTo enhance the accuracy of speech emotion recognition using multilevel features, it is essential to simultaneously integrate emotional information and reduce distribution mismatches among multilevel features.
Cheng Zha, Yuzang Tang
doaj +1 more source
Supply Chain Complexity – A Bibliometric Analysis
, 2020 Supply chain (SC) structures become more dynamic and complex with an increasing globality. Complexity in SCs relates to three main dimensions. Spatial, horizontal, and vertical complexity are associated with higher uncertainty and missing transparency in
Tiggemann, Jonas +3 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Systemic Risk and the Ripple Effect in the Supply Chain [PDF]
, 2019 Supply chains are highly complex systems, and disruptions may ripple through these systems in unexpected ways, but they may also start in unexpected ways. We investigate the causes of ripple effect through the lens of systemic risk.
Jennifer Blackhurst +3 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source