Results 61 to 70 of about 1,687,730 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Speech Emotion Recognition Based on Simultaneously Fusing and Transferring of Multilevel Speech Features

Journal of Electrical and Computer Engineering
To enhance the accuracy of speech emotion recognition using multilevel features, it is essential to simultaneously integrate emotional information and reduce distribution mismatches among multilevel features.
Cheng Zha, Yuzang Tang
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Building digital platform ecosystems: A synthetization of fundamental design topics from a literature review

Digital Business
The purpose of this paper is to contribute to the existing body of research on digital platforms by adopting an ecosystem perspective and considering an established framework. Through our work, we synthesize previous findings related to digital platforms
Thomas Goertler, Marcel Papert, Isabel Fischer, Malou Schmidt   +3 more
doaj   +1 more source

Costing the supply chain for delivery of ACT and RDTs in the public sector in Benin and Kenya [PDF]

, 2015
Studies have shown that supply chain costs are a significant proportion of total programme costs. Nevertheless, the costs of delivering specific products are poorly understood and ballpark estimates are often used to inadequately plan for the budgetary ...
Anupindi, Ravi, de Savigny, Don, Doumbia, Seydou, Johnson, Brittany, Shretta, Rima, Smith, Lisa, Yadav, Prashant   +6 more
core   +5 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Understanding Young Consumers’ E-Waste Recycling Behaviour in Bangladesh: A Developing Country Perspective

Recycling
The rising amount of electronic waste (e-waste) presents serious threats to the environment and public health. Addressing this challenge necessitates a focus on improving the e-waste recycling rate, which is facilitated by consumers’ spontaneous ...
Md Hasibul Islam, Md. Tamzidul Islam, Mohammad Rashedul Hoque, Shahnaz Zarin Haque, Bikash Barua, M. M. Obaidul Islam, Md. Faruque Hossain   +6 more
doaj   +1 more source

Cross-departmental collaboration in strategic sourcing as a catalyst for supplier development: The case of Eskom

Acta Commercii, 2017
Objective: The objective was to analyse the integration of and collaboration between strategic sourcing and supplier development at Eskom, South Africa’s primary electricity supplier, and to determine how strategic sourcing can be a catalyst for supplier
Mzoxolo E. Mbiko, Tatenda Mbara, Elana Swanepoel   +2 more
doaj   +1 more source

Shipbuilding 4.0 Index Approaching Supply Chain [PDF]

, 2019
The shipbuilding industry shows a special interest in adapting to the changes proposed by the industry 4.0. This article bets on the development of an index that indicates the current situation considering that supply chain is a key factor in any type ...
Aguayo, Alejandro J. Sánchez Sotano, Francisco J. Abad Fraga, Kumar, Lara, Maccari, Magdalena Ramirez-Peña, Mello, Moises Batista, Plinta, Porter, Ramirez-Peña, Rice, Saarni, Taylor, Womack, Womack   +16 more
core   +2 more sources