Results 41 to 50 of about 3,300,319 (310)

Covid-19 customer experiences of self-service technology across pharmacies in South Africa

Cogent Social Sciences, 2023
Using time-series data over a period of twelve months, Atlas.ti was employed to analyse the data extracted from Hello Peter, a South African online customer review and business platform, to assess Covid-19 customer reactions to e-services across South ...
Sebonkile Thaba, Lunga Jacobs, Adrien Ilumbe Laby   +2 more
doaj   +1 more source

Triple-A Supply Chains: The Bridge Between Supply Chain Analytics and Supply Chain Resilience

IEEE Transactions on Engineering Management
This study explores the critical interplay between Supply Chain Analytics, the Triple-A supply chain framework (agility, adaptability, and alignment), and Supply Chain Resilience (SCR), addressing a significant gap in both theory and practice. While SCA has emerged as a transformative tool for managing disruptions through data-driven insights, its ...
Muhammad Zia Ul Haq, Tahir Abbas Syed, Usman Akbar, Haris Aslam   +3 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Corporate social responsibility in buyer-supplier relationships : is it beneficial for top-tier suppliers to market their capability to ensure a responsible supply chain? [PDF]

The Retail and Marketing Review, 2014
This study assesses how top-tier suppliers market their capabilities to ensure a responsible upstream sup- ply chain to their downstream buyers, and how the marketing of corporate social responsibility (CSR)- related supply management practices affects ...
T Leppelt, K Foerstl, E Hartmann
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Segmentation of health-care consumers: psychological determinants of subjective health and other person-related variables

BMC Health Services Research, 2020
Background There is an observable, growing trend toward tailoring support programs – in addition to medical treatment – more closely to individuals to help improve patients’ health status.
Sjaak Bloem, Joost Stalpers, Edward A. G. Groenland, Kees van Montfort, W. Fred van Raaij, Karla de Rooij   +5 more
doaj   +1 more source

Working Capital Behavior of Firms during an Economic Downturn: An Analysis of the Financial Crisis Era

International Journal of Financial Studies, 2022
In times of crisis, cash and liquidity play an essential role. This paper analyzes the working capital measures over the course of a business cycle. We examine (1) how companies behave in economic downturns regarding their working capital components and (
Erik Hofmann, Juuso Töyli, Tomi Solakivi   +2 more
doaj   +1 more source