Results 51 to 60 of about 518,164 (317)

Integrating Healthcare Processes Through Supply Chain Principles [PDF]

open access: yes, 2023
Healthcare supply chain has increasingly attracted the attention of scholars, researchers, government officials, and clinicians as one of the primary strategies in their efforts to reduce healthcare costs while improving quality.
Altabsh, Mariam
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Segmentation of health-care consumers: psychological determinants of subjective health and other person-related variables

open access: yesBMC Health Services Research, 2020
Background There is an observable, growing trend toward tailoring support programs – in addition to medical treatment – more closely to individuals to help improve patients’ health status.
Sjaak Bloem   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Working Capital Behavior of Firms during an Economic Downturn: An Analysis of the Financial Crisis Era

open access: yesInternational Journal of Financial Studies, 2022
In times of crisis, cash and liquidity play an essential role. This paper analyzes the working capital measures over the course of a business cycle. We examine (1) how companies behave in economic downturns regarding their working capital components and (
Erik Hofmann   +2 more
doaj   +1 more source

Supply chain digitalization and performance: A moderated mediation of supply chain visibility and supply chain survivability

open access: yesHeliyon
The COVID-19 crisis has notably impacted global supply chains as it has disrupted manufacturing operations. To recover from the aforementioned disruptions, supply chain digitalization [SCD] is increasingly being acknowledged to help the recovery process.
Abdelwahab Al Tera   +2 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Systemic Risk and the Ripple Effect in the Supply Chain [PDF]

open access: yes, 2019
Supply chains are highly complex systems, and disruptions may ripple through these systems in unexpected ways, but they may also start in unexpected ways. We investigate the causes of ripple effect through the lens of systemic risk.
Jennifer Blackhurst   +3 more
core   +2 more sources

The Supply Chain Workforce: The Foundation of Health Supply Chains

open access: yesGlobal Health: Science and Practice
The articles in this supplement delve into the most pertinent topics in human resources for supply chain management (SCM), offering case studies and insights that exemplify best practices to strengthen the capacity of the health SCM workforce, support well-functioning health systems and increase access to health commodities.
Zwinkels, Dominique   +4 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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