Results 51 to 60 of about 3,810,215 (317)

The Supply Chain Workforce: The Foundation of Health Supply Chains

Global Health: Science and Practice
The articles in this supplement delve into the most pertinent topics in human resources for supply chain management (SCM), offering case studies and insights that exemplify best practices to strengthen the capacity of the health SCM workforce, support well-functioning health systems and increase access to health commodities.
Zwinkels, Dominique, Matowe, Lloyd, Asingizwe, Domina, Brown, Andrew N., Moody, Jonathan   +4 more
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Segmentation of health-care consumers: psychological determinants of subjective health and other person-related variables

BMC Health Services Research, 2020
Background There is an observable, growing trend toward tailoring support programs – in addition to medical treatment – more closely to individuals to help improve patients’ health status.
Sjaak Bloem, Joost Stalpers, Edward A. G. Groenland, Kees van Montfort, W. Fred van Raaij, Karla de Rooij   +5 more
doaj   +1 more source

Working Capital Behavior of Firms during an Economic Downturn: An Analysis of the Financial Crisis Era

International Journal of Financial Studies, 2022
In times of crisis, cash and liquidity play an essential role. This paper analyzes the working capital measures over the course of a business cycle. We examine (1) how companies behave in economic downturns regarding their working capital components and (
Erik Hofmann, Juuso Töyli, Tomi Solakivi   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Innovation in humanitarian logistics and supply chain management: a systematic review

, 2023
The COVID-19 global health crisis forced border closings, strained resources and tightened funding, forcing humanitarian organisations to innovate. This paper aims to identify gaps in the literature on innovation in humanitarian supply chains, and to ...
Heaslip, G, Vaillancourt, Alain, Tatham, P, Altay, N, Tatham, Peter, Kovács, G, Heaslip, Graham, Spens, K, Vaillancourt, A, Kovács, Gyöngyi, Altay, Nezih, Spens, Karen, Karen Spens, Nezih Altay, Gyöngyi Kovács, Graham Heaslip, Alain Vaillancourt, Peter Tatham   +17 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Can Blockchain Advance Digital Social Responsibility in Enterprise Ecosystems? Evidence From 121 Implementation Projects

Human Behavior and Emerging Technologies
This study explores how blockchain solutions impact digital social responsibility within enterprise ecosystems by impacting sustainable business practices and enabling mechanisms for responsible governance and stakeholder participation.
Tan Gürpinar, Alexander Grünewald, Maik Hausmann, Tobias Wappner   +3 more
doaj   +1 more source

Dynamic MAML with Efficient Multi-Scale Attention for Cross-Load Few-Shot Bearing Fault Diagnosis

Entropy
Accurate bearing fault diagnosis under various operational conditions presents significant challenges, mainly due to the limited availability of labeled data and the domain mismatches across different operating environments.
Qinglei Zhang, Yifan Zhang, Jiyun Qin, Jianguo Duan, Ying Zhou   +4 more
doaj   +1 more source