Results 141 to 150 of about 5,588,542 (410)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Study on Early Warning Methods for Shipping Input Risks Under Consideration of Public Health Events

Applied Sciences
The rapid expansion of economic globalization and trade has led to a sharp increase in the shipping investment risks currently faced by cities around the world.
Zhanxin Ma, Xiyu Zheng, Jiachao Wu, Dongping Pu   +3 more
doaj   +1 more source

Enhancing Supply Chain Visibility with Knowledge Graphs and Large Language Models [PDF]

arXiv
In today's globalized economy, comprehensive supply chain visibility is crucial for effective risk management. Achieving visibility remains a significant challenge due to limited information sharing among supply chain partners. This paper presents a novel framework leveraging Knowledge Graphs (KGs) and Large Language Models (LLMs) to enhance supply ...
arxiv  

Strategic Formation and Reliability of Supply Chain Networks [PDF]

arXiv, 2019
Supply chains are the backbone of the global economy. Disruptions to them can be costly. Centrally managed supply chains invest in ensuring their resilience. Decentralized supply chains, however, must rely upon the self-interest of their individual components to maintain the resilience of the entire chain.
arxiv  

Networked inventory management information systems: materializing supply chain management [PDF]

, 1996
Martin Verwijmeren, P. van der Vlist, Karel van Donselaar   +2 more
openalex   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Enhancing Supply Chain Visibility with Generative AI: An Exploratory Case Study on Relationship Prediction in Knowledge Graphs [PDF]

arXiv
A key stumbling block in effective supply chain risk management for companies and policymakers is a lack of visibility on interdependent supply network relationships. Relationship prediction, also called link prediction is an emergent area of supply chain surveillance research that aims to increase the visibility of supply chains using data-driven ...
arxiv  

Supply Chain Management Based on Market Mechanism in Virtual Enterprise [PDF]

, 1999
Toshiya Kaihara
openalex   +1 more source

Sustainable Supply Chains: Introduction

, 2016
As firms become progressively more tightly coupled in global supply chains, rather than being large vertically integrated monoliths, risks and opportunities associated with activities, upstream or downstream, will increasingly impinge upon their own well-being.
Bouchery, Yann, Corbett, Charles J, Fransoo, Jan C, Tan, Tarkan   +3 more
openaire   +3 more sources

Cluster Development and Knowledge Exchange in Supply Chain

, 2008
Industry cluster and supply chain are in focus of every countries which rely on knowledge-based economy. Both focus on improving the competitiveness of firm in the industry in the different aspect.
Bouras, Abdelaziz, Buzon, Laurent, Chakpitak, Nopasit, Sureephong, Pradorn   +3 more
core   +1 more source