Results 61 to 70 of about 561,297 (356)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Supply chain resource integration method under 4PL mode based on associated data

Journal of Applied Science and Engineering
The relevance of power supply chain resources is a key factor affecting the hit rate of resource integration. Therefore, a 4PL mode based supply chain resource integration method based on associated data is proposed. Firstly, analyze the functions of the
Huayu Chu, Lichong Cui, Yuejia Li, Lei Su, Yanyang Fu, Yuxiang Wang   +5 more
doaj   +1 more source

AN EXPLORATORY APPROACH TO INTEGRATION OF BUSINESS PRACTICES IN SUPPLY CHAIN MANAGEMENT [PDF]

Annals of the University of Oradea: Economic Science, 2014
Literature on supply chain management focuses increasingly on the topic of supply chain integration. Morash and Bowersox (1989) show that integration links relationships, activities, functions, processes and locations.
Constangioara Alexandru, , ,
doaj  

Investigating supply chain performance and supply chain integration linkage in Jordanian manufacturing firms. [PDF]

, 2018
Supply chain integration plays a major role in the success of any organisation. As a result in last over a decade it has drawn a significant interest from the research community and practitioners alike.
Garza-Reyes, Jose Arturo, Kumar, Vikas, Kumari, Archana, Tupa, Jiri, Zeidan, Jack   +4 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

How Can Vietnamese Companies Benefit from Management Accounting Systems and Supply Chain Integration Under Business Environment Uncertainty?

SAGE Open
We develop and test a moderated mediation model to explain how management accounting systems impact supply chain integration and firm performance, and how perceived environmental uncertainty influences these relationships.
Le Thi Thu Hieu, Nguyen Phong Nguyen, Tu Thanh Hoai   +2 more
doaj   +1 more source

E-supply chain integration adoption: examination of buyer–supplier relationships [PDF]

, 2018
The purpose of this study is to empirically examine the adoption of e-supply chain integration by electrical and electronic industry suppliers. This study has integrated both the transaction cost and resource-dependence models in understanding the ...
Chang H., Chong AYL., Duvall M., Geunes J, Hair JF, Pfeffer J, Singh PJ, Subramani M., Williamson OE., Ying W.   +9 more
core   +2 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Factors Affect To Supply Chain Efficiency

Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2020
The aim of this study is to investigate the relationship of supply chain integration (SCI), supply chain information sharing (IS) and supply chain performance (SCP).
Huỳnh Thị Phương Lan, Đường Võ Hùng, Nguyễn Thị Hồng Đăng   +2 more
doaj  

A collaboration framework to support decision making in new product development with the supply chain [PDF]

, 2013
Management use the supply chain features more frequently, as the increasing rate of product introduc-tions demands more efforts from a business to deliver new products effectively and efficiently.
Gao, James X., Hasan, Syed, Shah, Satya
core