Results 41 to 50 of about 123,299 (269)

Benchmarking criteria for evaluating third-party logistics providers in South Africa

Journal of Transport and Supply Chain Management, 2017
Background: In South Africa, deemed the ‘gateway to Africa’, there is limited evidence of the existence of a survey ranking third-party logistics providers (3PLs).
Claudia Karrapan, Mndeni Sishange, Elana Swanepoel, Peter J. Kilbourn   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Speech Emotion Recognition Based on Simultaneously Fusing and Transferring of Multilevel Speech Features

Journal of Electrical and Computer Engineering
To enhance the accuracy of speech emotion recognition using multilevel features, it is essential to simultaneously integrate emotional information and reduce distribution mismatches among multilevel features.
Cheng Zha, Yuzang Tang
doaj   +1 more source

Building digital platform ecosystems: A synthetization of fundamental design topics from a literature review

Digital Business
The purpose of this paper is to contribute to the existing body of research on digital platforms by adopting an ecosystem perspective and considering an established framework. Through our work, we synthesize previous findings related to digital platforms
Thomas Goertler, Marcel Papert, Isabel Fischer, Malou Schmidt   +3 more
doaj   +1 more source

Kaizen practices and performance improvement in Zambian manufacturing companies

Cogent Engineering, 2023
There is strong evidence that Zambian manufacturing organisations are increasingly implementing Kaizen programs to help them improve productivity and enhance delivery performance.
Chanda Sichinsambwe, Peter Lubosi Simasiku, Shem Sikombe, Harris Nyimbili   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Understanding Young Consumers’ E-Waste Recycling Behaviour in Bangladesh: A Developing Country Perspective

Recycling
The rising amount of electronic waste (e-waste) presents serious threats to the environment and public health. Addressing this challenge necessitates a focus on improving the e-waste recycling rate, which is facilitated by consumers’ spontaneous ...
Md Hasibul Islam, Md. Tamzidul Islam, Mohammad Rashedul Hoque, Shahnaz Zarin Haque, Bikash Barua, M. M. Obaidul Islam, Md. Faruque Hossain   +6 more
doaj   +1 more source

Taxonomy of digital signage message execution and media placement considerations [PDF]

The Retail and Marketing Review, 2020
Digital signage is a commercial promising field in marketing. Yet, it is a little researched topic, with an incomplete understanding of the factors to consider when planning digital signage message executions or media placements.
E M Xaba, AT Roux, GAP Drotsky
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source