Results 71 to 80 of about 16,368,583 (255)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Applied Sciences, 2018 Interest in smart factories and smart supply chains has been increasing, and researchers have emphasized the importance and the effects of advanced technologies such as 3D printers, the Internet of Things, and cloud services.
Byung Do Chung +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Description of the theoretical framework for a 'Consumer driven and responsive supply chain' [PDF]
, 2008 The strategic objective of this project is to increase fruit consumption and thereby improve the health and well-being of Europeans and their environment, by taking a total chain approach and identifying bottlenecks and opportunities in the fruit chain ...
Verdouw, C.N.
core
Green Supply Chain Network Design with Economies of Scale and Environmental Concerns
Journal of Advanced Transportation, 2017 This study considers a design problem in the supply chain network of an assembly manufacturing enterprise with economies of scale and environmental concerns. The study aims to obtain a rational tradeoff between environmental influence and total cost.
Dezhi Zhang +3 more
doaj +1 more source
Jurnal Aplikasi Bisnis dan Manajemen, 2020 The article described the difficulty to spot specific suppliers that feed the targeted customers in a closed-loop supply chain. When managers had difficulties in identifying the role of suppliers in a supply chain network, several possible situations ...
Hidajat Hendarsjah +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Security Modeling on the Supply Chain Networks [PDF]
Journal of Systemics, Cybernetics and Informatics, 2007 In order to keep the price down, a purchaser sends out the request for quotation to a group of suppliers in a supply chain network. The purchaser will then choose a supplier with the best combination of price and quality. A potential supplier will try to
Marn-Ling Shing +3 more
doaj