Results 61 to 70 of about 57,971 (259)

A Multi-Period Supply Chain Network Design for Biodiesel Fuels: The Case of Turkey

Gazi Üniversitesi Fen Bilimleri Dergisi, 2018
A major portion of energy consumed worldwide is derived from non-renewable energy sources. According to the International Energy Agency (IEA), the oil reserves that can meet the rising global oil demand around 1.7 trillion barrels, which may last about ...
Enis Baris KARAKOC, Berk AYVAZ, Ali Osman KUSAKCI, Fatih OZTURK   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

An uncertain sustainable supply chain network design for regulating greenhouse gas emission and supply chain cost

Cleaner Logistics and Supply Chain
The increasing global concern for sustainability in supply chain management is driven by stricter government regulations addressing environmental pollution and social injustice. This has led to a growing emphasis on integrating sustainability into supply
Amit Kumar, Kaushal Kumar
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Dynamic Supply Chain Design and Operations Plan for Connected Smart Factories with Additive Manufacturing

Applied Sciences, 2018
Interest in smart factories and smart supply chains has been increasing, and researchers have emphasized the importance and the effects of advanced technologies such as 3D printers, the Internet of Things, and cloud services.
Byung Do Chung, Sung Il Kim, Jun Seop Lee   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Green Supply Chain Network Design with Economies of Scale and Environmental Concerns

Journal of Advanced Transportation, 2017
This study considers a design problem in the supply chain network of an assembly manufacturing enterprise with economies of scale and environmental concerns. The study aims to obtain a rational tradeoff between environmental influence and total cost.
Dezhi Zhang, Fangzi Zou, Shuangyan Li, Lingyun Zhou   +3 more
doaj   +1 more source

NETWORK DESIGN DECISION IN A CLOSED LOOP SYSTEM: LESSON LEARNED FROM ELECTRICITY DISTRIBUTION POLICY IN INDONESIA

Jurnal Aplikasi Bisnis dan Manajemen, 2020
The article described the difficulty to spot specific suppliers that feed the targeted customers in a closed-loop supply chain. When managers had difficulties in identifying the role of suppliers in a supply chain network, several possible situations ...
Hidajat Hendarsjah, Wisnu Untoro, Reza Rahardian   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source