Results 51 to 60 of about 16,368,583 (255)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Supply chain vulnerability assessment: A network based visualization and clustering analysis approach [PDF]
, 2018 Supply chains are large, complex, and often unpredictable. Purchasing and supply managers and supply chain risk managers need methods and tools to enable them to quickly understand how unexpected disruptions in the supply chain start and grow and to what
Rungtusanatham, M. Johnny +3 more
core
A systems approach for modelling supply chain risks [PDF]
, 2013 Purpose – With increasing exposure to disruptions, it is vital for supply chains to manage risks proactively. Prediction of potential failure points and overall impact of these risks is challenging.
Michael Chester (164965) +7 more
core +1 more source
International Journal of Industrial Engineering and Production Research, 2016 Flexible and dynamic supply chain network design problem has been studied by many researchers during past years. Since integration of short-term and long-term decisions in strategic planning leads to more reliable plans, in this paper a multi-objective ...
Arash Nobari +2 more
doaj
Closed loop supply chain mathematical modeling considering lean agile resilient and green strategies
Croatian Operational Research Review, 2020 The supply chain management is planning, implementation and effective control of supply chain operations considered as a key factor for the competitiveness of the organizations.
Masoud Mohammadzadeh +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
An agent-based dynamic information network for supply chain management [PDF]
, 2004 One of the main research issues in supply chain management is to improve the global efficiency of supply chains. However, the improvement efforts often fail because supply chains are complex, are subject to frequent changes, and collaboration and ...
Lee, H, Ahn, H
core +1 more source
Big Data Analytics for controlling supply chain performance
, 2021 Congestion delay produces logistical consequences for the supply chain performance for stored goods. A delayed delivery produces disruption at the next level in the supply chain. To deal with this problem, the study demonstrate the use of Google data, in
Riemer, Torben, Warnke, Phillip
core +1 more source