Results 151 to 160 of about 1,391,443 (312)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Identification and classification of risks in the New Zealand plywood supply chain : thesis presented in fulfilment of the requirements for the degree of Master of Supply Chain Management at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2016
Activities in the supply chain cover a wide-ranging area from upstream to downstream in order to deliver products and services to end customers. Because of the supply chain’s width and scope, the activities in it consume a substantial portion of total
Kusumamurni, Pimpin
core  

ADOPTION OF ARTIFICIAL INTELLIGENCE AND DIGITAL SUPPLY CHAIN FOR ENHANCING SUPPLY CHAIN PERFORMANCE: MEDIATING ROLE OF GREEN SUPPLY CHAIN PROCESS

open access: yesOperational Research in Engineering Sciences: Theory and Applications
: Research empirically tested the impact of artificial intelligence adoption and digital supply chains on supply chain performance with the mediating effect of green supply chain process of manufacturing companies in Saudi Arabia.
Abdulaziz Aljoghaiman, Sanjar Mirzaliev
doaj   +2 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

The Relationship of Information Systems, Supply Chain Management With Organisational Performance [PDF]

open access: yes
Purpose In today’s world, Supply Chain Management (SCM) is a key strategic factor for increasing organisational effectiveness and for better realisation of organisational goals such as competitiveness, better customer care
Argyropoulou, M., Reid, Iain
core  

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Coordination and synchronization of material flows in supply chains: an analytical approach. [PDF]

open access: yes
The coordination of joint material flows is a key element in supply chain management. Although analytical models for the coordination of materials are of great practical value, literature analyzing them remains scarce.
De Boeck, Liesje, Vandaele, Nico
core  

The Influence of Supply Chain Digitalization on Integration and Agility in Company Performance

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the effect of supply chain digitalization on integration and agility in company performance. Supply chain digitalization is considered a key factor in improving operational efficiency and effectiveness.
Ikrima Ikrima   +2 more
doaj   +1 more source

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