Results 81 to 90 of about 1,279,777 (376)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Supply Chain Risk Prevention and Control Based on Fuzzy Influence Diagram and Discrete Hopfield Neural Network

open access: yesDiscrete Dynamics in Nature and Society, 2021
Efficient and reasonable supply chain management helps enterprises improve their efficiency, reduce costs, shorten cash flow times, and reduce enterprise risks. Risk prevention and control is a safety symbol for supply chains.
Xin Su, Maohua Zhong
doaj   +1 more source

Pengaruh Supply Chain Visibility, Supply Chain Flexibility, Supplier Development, Dan Inventory Control Terhadap Supply Chain Effectiveness Dengan Risk Management Culture Sebagai Variabel Moderating Pada PT Sulindo [PDF]

open access: yes, 2019
Penelitian ini bertujuan untuk mengetahui pengaruh supply chain visibility terhadap supply chain effectiveness, untuk mengetahui pengaruh supply chain flexibility terhadap supply chain effectiveness, untuk mengetahui pengaruh supplier development ...
Saputra, D. (Deni)
core  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

The central tendency of the seaport-fulcrum supply chain risk in Indonesia using a rough set

open access: yesAsian Journal of Shipping and Logistics, 2022
Seaports are crucial in modern global supply chain networks and systems, exerting a significant impact on the ecological area's economy. Supply chain entities play a substantial integration role, and potential threats at seaports harm chain continuity ...
Muhammad Reza Do. Bagus, Shinya Hanaoka
doaj  

Option contracts in fresh produce supply chain with circulation loss [PDF]

open access: yes, 2013
Purpose: The purpose of this paper is to investigate management decisions via option contracts in a two-stage supply chain in which a fresh produce supplier sells to a retailer, considering the circulation loss of the fresh produce. Design/methodology/
Chen, Xu, Wang, Chong
core   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Dairy Supply Chain Risk Management in Bangladesh: Field studies of Factors and Variables

open access: yesJurnal Teknik Industri, 2014
Supply chain risk management (SCRM) has gained wide attention among the academia and the business community in the present competitive business world.
Tasnuba Nasir   +2 more
doaj  

Evolutionary Game Dynamics for Financial Risk Decision-Making in Global Supply Chain

open access: yesComplexity, 2018
This paper focuses on the game evolution process and its influencing factors of financial risk cooperation behavior between suppliers and manufacturers in global supply chain system.
Zhi Li, Guanghao Jin, Shen Duan
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

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