Results 81 to 90 of about 783,343 (331)
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Evolutionary Game Dynamics for Financial Risk Decision-Making in Global Supply Chain
Complexity, 2018 This paper focuses on the game evolution process and its influencing factors of financial risk cooperation behavior between suppliers and manufacturers in global supply chain system.
Zhi Li, Guanghao Jin, Shen Duan
doaj +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Chemical Fuel Supply Chain Integration and Optimization under the Influence of Uncertain Factors
Chemical Engineering Transactions, 2018 The petrochemical industry belongs to the dangerous chemical industry. The optimization of supply chain can significantly improve the overall profits of enterprises, reducing costs and risks.
Liu Liu
doaj +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Chemical Emergency Supply Chain Risk Evaluation and Mitigation for Major Natural Disasters
Chemical Engineering Transactions, 2017 The operation of the chemical emergency supply chain may be destroyed by the risk events, such as major natural disasters and other emergencies, which can bring about the decreasing of node operating capacity.
Dali Jiang +4 more
doaj +1 more source
Prioritization of Risks in Supply Chains
, 2009 Modern supply chains are very complex, with physical, financial, and information flows occurring simultaneously in order to ensure that products are delivered in the right quantities, to the right place in a cost-effective manner. Maintaining uninterrupted supply chain flows is a prerequisite for the success of a supply chain in the marketplace.
openaire +2 more sources
Supply chain risk perception: understanding the gap between theory and practice. [PDF]
, 2018 The risks inherent in the supply chain threaten the effectiveness and the output of the chain. It is capable of hampering the growth and performance of organizations whose goods pass through a supply chain.
Adebola Adeseun, Maria +3 more
core +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Cogent Business & ManagementThis paper aims to assess the effect of inventory control systems on performance of mining firms in Zimbabwe. A systematic literature review was used to review current and relevant scholarly work.
Dumisani Mawonde +3 more
doaj +1 more source