Results 61 to 70 of about 234,692 (339)

Stochastic Supply Chain Optimization with Risk Management

Chemical Engineering Transactions, 2019
This paper presents the hypothetical case study of supply-chain management of the carbon dioxide-utilization products where its feedstock is sewage gas containing mostly methane and CO2. This supply chain begins with three suppliers sending sewage gas of
Narut Suchartsunthorn, Kitipat Siemanond
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Evaluation of supply chain risks by fuzzy DEMATEL method: a case study of iron and steel industry in Turkey

International Journal of Production Management and Engineering, 2022
Business practices to strengthen competitiveness increase the vulnerability of supply chains to risks. Risks that can adversely affect the effectiveness and efficiency of supply chain activities are events that disrupt the flow of information, materials,
Asuman Üstündağ, Sinan Çıkmak, Merve Çankaya Eyiol, Mustafa Cahit Ungan   +3 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Meminimasi Risiko pada Rantai Pasok Menggunakan Kerangka Kerja Suplly Chain Risk Management di PT. Adhi Chandra Dwiutama

Rekayasa Hijau: Jurnal Teknologi Ramah Lingkungan, 2019
ABSTRAK Rantai Pasok merupakan jaringan dari perusahaan- perusahaan yang bekerja secara bersama untuk menciptakan dan mengantarkan suatu produk ke konsumen akhir.
Arief Irfan Syah Tjaja, Dio Rizcki Sekartyasto, Arif Imran   +2 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Supply Chain Disruption Models: A Critical Review

Logistics Research, 2018
Enterprises affected by supply chain disruptions have reported adverse consequences and dramatic financial losses. Within the research area of supply chain risk management, researchers use simulation models and algorithms to analyze disruption risks ...
Niels Bugert, Rainer Lasch
doaj   +1 more source

Research on key nodes identification of aviation manufacturing supply chain based on complex network

Hangkong gongcheng jinzhan, 2023
With the increasing instability and the participation of more participants in the aviation manufacturing supply chain,the risks faced by the management of the aviation manufacturing supply chain is also increased.
HUANG Hui, LI Ruiqi
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source