Results 91 to 100 of about 4,116,789 (307)

Implementing recovery resources in trauma care: impact and implications

open access: yesOTA International, 2019
. Objectives:. To identify resources that patients perceive as helpful to their recovery and to characterize the impact of the Trauma Survivor Network (TSN), a program committed to enhancing recovery through education and engagement. Design:. Prospective
Natasha M. Simske, BS   +4 more
doaj   +1 more source

Effect of an advocacy intervention on mental health in Chinese women survivors of intimate partner violence: A randomized controlled trial [PDF]

open access: yes, 2010
Context: Intimate partner violence (IPV) against women can have negative mental health consequences for survivors; however, the effect of interventions designed to improve survivors' depressive symptoms is unclear.
Bullock, L   +6 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Comparison of Three-Dimensional Motion During Side-Step Cutting in Pediatric Athletes with Recent ACL Reconstruction and those with No ACL Surgical History

open access: yesOrthopaedic Journal of Sports Medicine, 2015
Objectives: This study assessed differences between pediatric athletes’ anterior cruciate ligament (ACL) reconstructed limb and non-reconstructed limb compared to limbs with no lower extremity surgical history during a side-step cut.
James Lee Pace MD   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Damage Control Laparotomy in Trauma Patients: A Level I Trauma Center Experience

open access: yesAlbanian Journal of Trauma and Emergency Surgery
Introduction: The surgical management of traumatic injury is an evolving and controversial topic. We present outcomes of laparotomy performed for blunt and penetrating trauma at a level I trauma center over a nearly 10-year period. Material and Methods:
Anthony J. Duncan   +2 more
doaj   +1 more source

Need to improve awareness and treatment compliance in high-risk patients for diabetic complications in Nepal [PDF]

open access: yes, 2018
Objective/introduction It is known that knowledge, awareness, and practice influence diabetic control. We compared factors pertaining to healthy lifestyle (exercising, avoiding smoking), self-help (attending appointments, following treatment regimens ...
Gurung, Govind   +5 more
core   +1 more source

Aesthetic Outcome and Patient Perception of Immediate vs. Delayed Loading of Implant-Supported Single Crowns: A Randomized Controlled Trial

open access: yesJournal of Pharmacy and Bioallied Sciences
ABSTRACT Background: This randomized controlled trial aimed to compare the aesthetic outcome and patient perception of immediate versus DL of implant-supported single crowns. Methods: A total of 60 patients with a single missing tooth were enrolled
Mukesh Kumar   +5 more
openaire   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

A study of pharmacists-joint total parenteral nutrition in haematopoietic cell transplantation in accord with diagnosis related groups: A retrospective clinical research

open access: yesJournal of Pharmaceutical Policy and Practice
Background Within Diagnosis Related Groups, based on service capability, efficiency, and quality safety assessment, clinical pharmacists contribute to promoting rational drug utilisation in healthcare institutions.
Le Yang, Lu-lu Qiu, Hui-yi Lv, Miao Li
doaj   +1 more source

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