Results 111 to 120 of about 1,767,596 (309)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Ecology and control of the trachoma vector Musca sorbens [PDF]

open access: yes, 2001
The work described in this thesis was conducted In rural Gambia and builds a body of evidence Incriminating the fly Musca sorbens as a vector of the blinding disease, trachoma, which is caused by ocular infection with Chlamydia trachomatis. Literature on
Emerson, Paul Michael
core  

An Effective Multiclass Twin Hypersphere Support Vector Machine and Its Practical Engineering Applications

open access: yes, 2019
Twin-KSVC (Twin Support Vector Classification for K class) is a novel and efficient multiclass twin support vector machine. However, Twin-KSVC has the following disadvantages. (1) Each pair of binary sub-classifiers has to calculate inverse matrices. (2)
Wenhui Wang   +4 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Gun Control after Heller: Litigating against Regulation [PDF]

open access: yes
The “core right” established in D.C. vs. Heller (2008) is to keep an operable handgun in the home for self-defense purposes. If the Court extends this right to cover state and local jurisdictions, the result is likely to include the elimination of the ...
Philip J. Cook, Jens Ludwig, Adam Samaha
core  

Usability of an mHealth-delivered physical activity intervention after mild stroke or transient ischemic attack: the role of therapist engagement and user barriers

open access: yesBMC Digital Health
Background Mobile Health (mHealth) is a promising tool for supporting long-term physical activity following stroke or transient ischaemic attack (TIA), but its usability in this population remains unclear.
David Moulaee Conradsson   +3 more
doaj   +1 more source

Effect of early enteral nutrition combined with probiotics on the therapeutic effect and prognosis of patients with severe multiple injuries

open access: yesZhongguo linchuang yanjiu
Objective To investigate the effect and prognosis of early enteral nutrition (EEN) combined with probiotics on patients with severe multiple injuries.
XU Hao*, TIAN Lin, ZHENG Xiangde
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Predictors of college student support for alcohol control policies and stricter enforcement strategies

open access: yes, 2008
Objectives: With alcohol-related problems remaining a concern on college campuses, prevention efforts are increasingly directed to addressing the environmental factors that encourage consumption.
Wood, Mark D.   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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