Results 131 to 140 of about 4,116,789 (307)

Effect of early enteral nutrition combined with probiotics on the therapeutic effect and prognosis of patients with severe multiple injuries

open access: yesZhongguo linchuang yanjiu
Objective To investigate the effect and prognosis of early enteral nutrition (EEN) combined with probiotics on patients with severe multiple injuries.
XU Hao*, TIAN Lin, ZHENG Xiangde
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

An empirical investigation of the antecedents of salesforce control systems

open access: yes, 2017
11 hypotheses from agency theory, transaction cost analysis, and Ouchi's theoretical approach on the impact of environmental, Company and salespeople characteristics on the design of salesforce control systems (outcome- vs. behavior-based) are summarized
Krafft, Manfred
core  

Could there be unintended effects of government support for seafood traceability implementation on business planning? Results of a survey among Italian fishery businesses [PDF]

open access: yes, 2016
Governments have intervened in food, agricultural and fisheries markets through various support programs to promote adoption of traceability practices and systems in order to raise food safety levels and increase industry competitiveness.
Asioli, Daniele, Boeker, Andreas
core  

Ceria-Zirconia Supported Catalysts for Air Pollution Control: Gold vs. Platinum.

open access: yes, 2017
Novel types of monometallic catalysts based on platinum or gold supported on ceria-zirconia mixed oxide were prepared and tested in the oxidation of different types of volatile organic compounds. It was shown that the type of noble metal, its particle size and/or loading are the key factors that influence the physicochemical properties of the catalysts
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Compression coil provides increased lead control in extraction procedures [PDF]

open access: yes, 2017
Aims We investigated a new lead extraction tool (Compression Coil; One-Tie, Cook Medical) in an experimental traction force study. Methods and results On 13 pacemaker leads (Setrox JS53, Biotronik) traction force testing was performed under different ...
Falk, Volkmar   +5 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Psychological Adaptation Issues and Nursing Strategies for Elderly Middle-Aged and Older Adults Patients with Diabetes

open access: yesPsychiatry and Clinical Psychopharmacology
Background: To investigate the effects of a comprehensive nursing intervention program oriented toward psychological adaptation on blood glucose control, psychological status, and self-management capabilities in middle-aged and elderly diabetic patients
Chunhua Diao
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy