Results 131 to 140 of about 8,098,927 (284)

Affect and decision making: A ”hot” topic

open access: yes, 2006
The seven papers in this special issue represent the breadth and complexity of approaches to the study of affect in judgment and decision processes. Four papers examine the role of arousal or specific emotions in decision making.
Slovic, P   +3 more
core  

Supported Decision Making With People at the Margins of Autonomy. [PDF]

open access: yesAm J Bioeth, 2021
Peterson A, Karlawish J, Largent E.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Decision Making in Geriatric Oncology: Supported Versus Assisted Decision Making [PDF]

open access: yesJournal of Clinical Oncology, 2021
Sabine Sommerlatte   +3 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A new Aged Care Act: Progress in implementing a supported decision-making approach in Australia’s Federation? [PDF]

open access: yes
This article evaluates the first legislative attempt by the Commonwealth to honour its commitments under the United Nations Convention on the Rights of Persons with Disabilities (‘CRPD’), by introducing a supported decision-making framework into the ...
Sinclair, Craig ; https://orcid.org/   +2 more
core  

Supported Decision Making in South America: Analysis of Three Countries' Experiences. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Vásquez Encalada A, Bialik K, Stober K.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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