Results 111 to 120 of about 8,098,927 (284)

AI-Supported lecturer decision-making in higher education: a socio-technical perspective

International Journal of Educational Technology in Higher Education
Artificial intelligence (AI) has become an integral part of teaching and learning in higher education. Through its capacity to generate actionable insights from student data, AI systems provide new opportunities to support lecturers’ decision-making ...
Melike Nur Köroğlu, Jonas Mayrhofer, Alexander Steinmaurer, Philipp Wintersberger, Sebastian Maximilian Dennerlein, Robert Weinhandl   +5 more
doaj   +1 more source

Evaluating the Effectiveness of AI-Supported Digital Training: Implications for Organizational Learning and Decision-Making

Administrative Sciences
In contemporary organizations, digital learning environments and AI-supported instructional modalities play an increasingly important role in workforce upskilling and operational efficiency.
Nemanja Kašiković, Sandra Dedijer, Željko Zeljković, Dragana Glušac, Velibor Premčevski, Aleksandar S. Anđelković, Nemanja Tasić   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Leveraging chatbots for enhanced decision-making: a comprehensive literature review

Frontiers in Artificial Intelligence
IntroductionChatbots using large language models such as ChatGPT, Google Bard, etc., have become increasingly popular in recent years. The chatbot’s ability to simulate conversations with users and process input data and respond based on that information
Phiwe M. Simelane, Phiwe M. Simelane, Javeed Kittur, Javeed Kittur   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Scanpath Analysis of the Risky Decision-Making Process

, 2016
In the field of eye tracking, scanpath analysis can reflect the sequential and temporal properties of the cognitive process. However, the advantages of scanpath analysis have not yet been utilized in the study of risky decision making.
Zhang, Yang-Yang, Wang, Wei, Liang, Zhu-Yuan, Wang, Zuo-Jun, Lei Zhou, Shu Li, Zhu-Yuan Liang, Li, Shu, Zuo-Jun Wang, Zhou, Lei, Li-Lin Rao, Xingshan Li, Wei Wang, Rao, Li-Lin, Yang-Yang Zhang, Li, Xingshan   +15 more
core   +1 more source

Supported decision making: Facilitating the self-determination of persons living with Alzheimer's and related diseases. [PDF]

J Am Geriatr Soc, 2023
Largent EA, Peterson A, Karlawish J.
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source