Results 101 to 110 of about 4,637,377 (303)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Psychopharmacology in supportive care of cancer: a review for the clinician. III. Antidepressants

, 2000
This review covers pharmacokinetics, adverse effects and drug interactions of antidepressants and the indications for them, with the aim of assisting the clinician working in palliative and supportive care in the prescription of such drugs.
Buclin, T., Mazzocato, C., Stiefel, F., Berney, A.   +3 more
core   +1 more source

Supportive care needs of Iranian cancer patients

, 2014
Background: A supportive needs assessment is an essential component of any care program. There is no research evidence regarding the supportive care needs of cancer patients in Iran or other Middle Eastern countries.
Pakpour, Vahid, Faranak Jabarzadeh, Rahmani, Azad, Ferguson, Caleb (R19103), Vahid Pakpour, Mohammadpoorasl, Asghar, Narges Moradi, Asghar Mohammadpoorasl, Azad Rahmani, Jabarzadeh, Faranak, Moradi, Narges, Caleb Ferguson   +11 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Supportive Care

, 2017
AbstractHematopoietic stem cell transplantation (HSCT) care is highly complex. This chapter focuses on the aspects of supportive care required following HSCT.Assessment tools are key component of nursing practice and are necessary for planning and providing patient-centered care.
S. J. van der Linden, M. E. G. Harinck, H. T. Speksnijder, Teija Schröder, Ien Schlösser, Vera Verkerk, Michaela van Bohemen, A. M. Rusman-Vergunst, J. C. Veldhuijzen, W. J. A. Quak   +9 more
openaire   +2 more sources

Acceptability and feasibility of a Patient Support Coordinator (PSC) model to facilitate serious illness communication in outpatient oncology

BMC Palliative Care
Background Conventional serious illness conversations (SICs) are frequently impeded by clinical time constraints and a lack of psychological readiness among patients.
Alston Ng, Su-Min Yeo, Wu Meng Tan, Bernard Chua, Rieka Erina, Shirlyn Hui Shan Neo   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

CaRE@ELLICSR: Effects of a clinically integrated, group‐based, multidimensional cancer rehabilitation program

Cancer Medicine
Background Although oncology clinical practice guidelines recognize the need and benefits of exercise, the implementation of these services into cancer care delivery remains limited. We developed and evaluated the impact of a clinically integrated 8‐week
Christian J. Lopez, Daniel Santa Mina, Victoria Tan, Manjula Maganti, Cheryl Pritlove, Lori J. Bernstein, David M. Langelier, Eugene Chang, Jennifer M. Jones   +8 more
doaj   +1 more source

Adapting and implementing the Serious Illness Care Programme for outpatient oncology, cardiology and palliative medicine clinics: a mixed-methods feasibility study

BMJ Open
Objectives To evaluate the feasibility of implementing a coordinator-facilitated Serious Illness Care Programme (SICP) in outpatient oncology, cardiology and palliative medicine clinics.Design Single-arm, mixed-methods, prospective feasibility study ...
Alston Ng, Su-Min Yeo
doaj   +1 more source

Defining Carers [PDF]

, 2015
The purpose of this paper is less to answer questions than to ask them, and less to define ‘carers’ than to understand who they are. In particular, its purpose is to ask why the label ‘family carer’ may be rejected by some of them, or by particular ...
Care Alliance Ireland
core   +1 more source