Results 11 to 20 of about 35,591 (294)

Preparations of Rectal Suppositories Containing Artesunate

Pharmaceutics, 2020
Rectal artesunate suppositories are a useful option for pre-referral treatment of severe malaria, specifically in children under 6 years of age in remote malaria-endemic areas.
Suzanne Persaud, Sandra Eid, Natalia Swiderski, Ioannis Serris, Hyunah Cho   +4 more
doaj   +2 more sources

Formulation and Optimization of Metronidazole and Lactobacillus spp. Layered Suppositories via a Three-Variable, Five-Level Central Composite Design for the Management of Bacterial Vaginosis

Pharmaceutics, 2022
Bacterial vaginosis, a polymicrobial clinical syndrome characterized by a shift in healthy vaginal microbiota due to bacterial colonization, is characterized by high recurrence rates after conventional treatment with an antimicrobial agent.
Margaret O. Ilomuanya, Busayo B. Salako, Modupe O. Ologunagba, Omonike O. Shonekan, Kruga Owodeha-Ashaka, Eseosa S. Osahon, Andrew N. Amenaghawon   +6 more
doaj   +2 more sources

Impact of Probiotic SYNBIO Administered by Vaginal Suppositories in Promoting Vaginal Health of Apparently Healthy Women [PDF]

Current Microbiology, 2016
The purpose of this study was to investigate whether vaginal administration of probiotic Lactobacillus results in their colonization and persistence in the vagina and whether it promotes normalization and maintenance of pH and Nugent score. A single-arm,
CECCHINI, Cinzia, Coata, Giuliana, COMAN, MARIA MAGDALENA, CRESCI, Alberto, Di Renzo, Gian Carlo, ORPIANESI, Carla, SILVI, Stefania, VERDENELLI, Maria Cristina   +7 more
core   +2 more sources

Release of Tenofovir from Carrageenan-Based Vaginal Suppositories

Pharmaceutics, 2014
Microbicides are an active area of research for HIV prevention, being developed as a woman-initiated method of prevention during unprotected coitus.
Toral Zaveri, John E. Hayes, Gregory R. Ziegler   +2 more
doaj   +2 more sources

A phase I study of intra-anal artesunate (suppositories) to treat anal high-grade squamous intraepithelial lesions

PLoS ONE, 2023
Background Ablation or surgical excision is the typical treatment of anal high-grade squamous intraepithelial lesions (HSIL). Recurrences are common due to the persistence of underlying human papillomavirus (HPV) infection.
S. H. Fang, M. Plesa, Evie H Carchman, Nicole A. Cowell, Emily Staudt, Kyleigh Twaroski, Ulrike K Buchwald, Cornelia L. Trimble   +7 more
semanticscholar   +1 more source

Modern Aspects of Suppositories: A Review

European Journal of Pharmaceutical Research, 2023
Suppositories are an underutilized dosage form. Suppositories are such types of dosage forms used to provide medication via the vaginal and rectal routes. Vaginal suppositories are commonly referred to as pessaries.
Aman Kumar, Arindam Kolay, Ujwal Havelikar   +2 more
semanticscholar   +1 more source

Preclinical Potential of Probiotic-Loaded Novel Gelatin–Oil Vaginal Suppositories: Efficacy, Stability, and Safety Studies

Gels, 2023
The current study describes a suppository base composed of aqueous gelatin solution emulsifying oil globules with probiotic cells dispersed within. The favorable mechanical properties of gelatin to provide a solid gelled structure, and the tendency of ...
Anchal Bassi, G. Sharma, P. Deol, R. Madempudi, I. Kaur   +4 more
semanticscholar   +1 more source

Clinical Background Factors as Predictors of the Efficacy of 5-Aminosalicylic Acid Suppositories in Patients with Ulcerative Colitis

Inflammatory Intestinal Diseases, 2023
Introduction: Although the efficacy of 5-aminosalicylic acid (ASA) suppositories for ulcerative colitis (UC) has been reported in many studies, many studies have also described poor adherence to 5-ASA suppository regimens.
Kazuhiko Uchiyama, Tomohisa Takagi, Katsura Mizushima, Kohei Asaeda, Mariko Kubota-Kajiwara, Takeshi Sugaya, Saori Kashiwagi, Yuki Minagawa, Yuma Hotta, Makoto Tanaka, Ken Inoue, Kazuhiro Katada, Kazuhiro Kamada, Takeshi Ishikawa, Hiroaki Yasuda, Hideyuki Konishi, Mitsuo Kishimoto, Yuji Naito, Yoshito Itoh   +18 more
doaj   +1 more source

Parents/Caregivers' perceptions towards use of analgesic suppositories in paediatric elective surgery

African Journal of Paediatric Surgery, 2023
Introduction: Despite the benefits of analgesic suppositories, there remains controversy around their administration. The perceptions of the parents and caregivers regarding this are unknown in our population.
Nondwe Mgoqo, Palesa Mogane, Palesa Motshabi Chakane   +2 more
doaj   +1 more source

DEVELOPMENT OF THE COMPOSITION AND TECHNOLOGY OF EXTEMPORANEOUS SUPPOSITORIES WITH СLINDAMYCIN AND SEA BUCKTHORN OIL [PDF]

Annals of Mechnikov's Institute, 2019
Introduction. Antibacterial therapy certainly plays an important role in the treatment of these pathologies, although in most cases it causes allergic states, antibiotic resistance of various types of microorganism strains, and also a disfunction of ...
Chushenko, V.M., Yarnykh, T.G., Osolodchenko, T.P., Yuryeva, G.B., Herasymova, I.V.   +4 more
doaj   +3 more sources