Comparison of physicochemical properties of suppositories containing starch hydrolysates
The purpose of this work was to determine the effect of starch hydrolysates (SH) on the physicochemical properties of suppositories. The study was conducted with suppositories with acetaminophen (AAP) a typical antipyretic analgesic, as model drug on ...
Piotr Belniak +4 more
doaj +1 more source
Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide [PDF]
BACKGROUND: For ≈ 24 years the AIDS pandemic has claimed ≈ 30 million lives, causing ≈ 14,000 new HIV-1 infections daily worldwide in 2003. About 80% of infections occur by heterosexual transmission.
A Robert Neurath +66 more
core +3 more sources
Management of erectile dysfunction post-radical prostatectomy [PDF]
© 2015 Saleh et al.Radical prostatectomy is a commonly performed procedure for the treatment of localized prostate cancer. One of the long-term complications is erectile dysfunction.
Abboudi, H +4 more
core +1 more source
The Potential of Allanblackia floribunda Butter as a Suppository Base [PDF]
The rectal route for drug administration is becoming attractive to drug formulators because there are no hepatic first-pass effects, it decreases gastrointestinal side effects, and it avoids undesirable food effects on drug absorption.
Mary Konadu +4 more
doaj +1 more source
Budesonide Foam Has a Favorable Safety Profile for Inducing Remission in Mild-to-Moderate Ulcerative Proctitis or Proctosigmoiditis. [PDF]
BackgroundBudesonide foam, a rectally administered, second-generation corticosteroid with extensive hepatic first-pass metabolism, is efficacious for the treatment of mild-to-moderate ulcerative proctitis and ulcerative proctosigmoiditis.AimThe aim of ...
Barrett, Andrew C +10 more
core +3 more sources
Firmness Perception Influences Women’s Preferences for Vaginal Suppositories
Microbicides are being actively researched and developed as woman-initiated means to prevent HIV transmission during unprotected coitus. Along with safety and efficacy, assessing and improving compliance is a major area of research in microbicide ...
Toral Zaveri +4 more
doaj +1 more source
Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad +4 more
core +1 more source
5-ASA Suppositories in Hemorrhoidal Disease
Forty patients with active hemorrhoidal disease were entered into this double-blind trial, 20 of whom were randomized to treatment with 5-aminosalicylic acid (5-ASA) (500 mg) suppositories.
P Gionchetti +5 more
doaj +1 more source
A Clinical Investigation of the Mechanism of Loxoprofen, a Non-steroidal Anti-inflammatory Drug, for Patients with Nocturia [PDF]
We previously reported the effectiveness of loxoprofen sodium (loxoprofen), a non-steroidal anti-inflammatory drug, for patients with lower urinary tract symptoms (LUTS) complaining of nocturia.
Araki, Motoo +3 more
core +1 more source
Studying structurally-mechanical characteristics suppositories with amlodipine
Rheological behaviour suppositories with amlodipine on lypofiles to a basis are studied and character of temperature effect on their structurally-mechanical properties is positioned.
Fadi Al Zedan +2 more
doaj +1 more source

