Results 81 to 90 of about 12,168 (219)

Effect of Age and Age‐Defined Menopausal Status on Linaclotide Efficacy and Safety in Adults With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: Post Hoc Analyses of Phase 2b/3 Studies

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 9, September 2026.
A post hoc pooled analysis of eight phase 2b/3 trials showed that linaclotide improved bowel and abdominal symptoms and was associated with a shorter time to response than placebo in adults with IBS‐C or CIC, irrespective of age or age‐defined menopausal status.
Lin Chang   +9 more
wiley   +1 more source

Application of Three‐Dimensionally Printed Surgical Guides in Precise Sacral Tumor Excision and Defect Reconstruction

open access: yesOrthopaedic Surgery, Volume 18, Issue 9, Page 1847-1860, September 2026.
Patient‐specific 3D‐printed guiding templates significantly improve surgical precision and efficiency in complex sacral tumor resection and reconstruction compared to conventional freehand techniques. This computer‐assisted workflow reduces operative time, intraoperative blood loss, and fluoroscopy frequency, providing a safer, highly reproducible ...
Yansong Liu   +7 more
wiley   +1 more source

RESEARCH ON MICROBIOLOGICAL PURITY OF “PHYTOPROST” AND “TAMSULOPROST” SUPPOSITORIES [PDF]

open access: yesAnnals of Mechnikov's Institute, 2014
Results of the tests on microbiological purity of the test samples of "Tamsuloprost" and "Phytoprost" suppositories for the treatment of prostate diseases have shown that no viable cells of fungi were found in the preparations, the number of viable ...
Gritsenko V. I.   +2 more
doaj  

Effectiveness of insulin suppositories in diabetic patients

open access: yes, 1989
Experimental insulin suppositories regulated postprandial hyperglycaemia in diabetic patients. The insulin suppositories seemed also to avoid hyperinsulinaemia.
Akira Kamada   +5 more
core   +1 more source

In-vitro and in-vivo availability of mebeverine hydrochloride suppositories

open access: yes, 2006
Mebeverine hydrochloride suppositories were prepared using Witepsol H15 suppository base. The effect of different concentrations of various enhancers (surfactants, amino acids and osmotic modifiers) on the drug release form the prepared suppositories was
Manal El-Khawaas   +2 more
core   +1 more source

PREPARATION AND IN VITRO EVALUATION OF FAST RELEASE DIAZEPAM SUPPOSITORIES FOR FEBRILE SEIZURES

open access: yes, 2017
  Objective: The objective of this study was to optimize the best formula for fast release suppositories of diazepam.Methods: Suppositories were prepared by fusion method using Witepsol H15 as oleaginous base, polyethylene glycol as water-soluble polymer
Aseel Alsamman, Mohammad Othman
core   +3 more sources

Suppositories in current therapy I [PDF]

open access: yes, 2011
Suppositories are a conventional dosage form. Although their research is not being developed much further, there are still some changes to be found. Some new adjuvants have been used, the old active substances have been deleted and replaced by new ones ...
Kočová, Alena
core  

Development of the composition and research of the equivalence of suppositories with diclofenac sodium by in vitro method using “Dissolution” test for lipophilic solid dosage forms

open access: yesZaporožskij Medicinskij Žurnal, 2019
The aim: Development of the composition and investigation of the equivalence of suppositories with sodium diclofenac by in vitro method on a device with a flow-through cell in accordance with modern requirements of SPhU.
O. O. Salii   +4 more
doaj   +1 more source

Preformulation studies on naproxen suppositories

open access: yes, 1994
The results of compatibility studies on a formulation for suppositories containing naproxen sodium, calcium levulinate and a fat base (Monoleno OH-6) are reported. Thermal analysis (DSC) was mainly used for preformulation studies on the components, their
Jixiong Yan   +5 more
core  

Preparation of suppositories with propolis extract [PDF]

open access: yes, 2018
Department of Drugs Technology, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of MoldovaIntroduction. Propolis is known as one of natural products with multiple therapeutic effects, such as: antimicrobial, antibiotic ...
Sofian, Irina
core   +1 more source

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