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Journal of the American Pharmaceutical Association (Scientific ed.), 1950
The utility and versatility as suppository base materials of polyoxyalkylene derivatives of sorbitan partial fatty acid esters are described. These nontoxic, nonirritant, nonionic surface-active materials are particularly adaptable to suppository base formulation.
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The utility and versatility as suppository base materials of polyoxyalkylene derivatives of sorbitan partial fatty acid esters are described. These nontoxic, nonirritant, nonionic surface-active materials are particularly adaptable to suppository base formulation.
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Suppositories are prepared using various methods, each tailored to ensure the appropriate incorporation and release of the active ingredient. The three primary methods of preparation are the molding method, the compression method, and the hand-rolling method.
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Metoclopramide suppository considerations
Drug Intelligence & Clinical Pharmacy, 1988J A, Tami, W W, Waite
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Suppositories are solid dosage forms intended for insertion into body orifices, where they melt, soften, or dissolve to exert local or systemic effects. Commonly used routes include rectal, vaginal, and urethral administration. They are designed to bypass the gastrointestinal tract, making them suitable for patients who cannot take oral ...
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