Results 41 to 50 of about 2,659,694 (301)

Influence of Atmosphere Near-Surface Layer Properties on Development of Cloud Convection

open access: yesAtmosphere, 2019
A two-dimensional mathematical model of moist air convection in the sub-cloud and cloud layers is proposed. A theoretical analysis of the influence of near ground atmospheric parameters on the development of sub-cloud and cloud convection is provided ...
Magomet T. Abshaev   +9 more
doaj   +1 more source

Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas

open access: yeseLife
The Trp53 gene encodes several isoforms of elusive biological significance. Here, we show that mice lacking the Trp53 alternatively spliced (AS) exon, thereby expressing the canonical p53 protein but not isoforms with the AS C-terminus, have unexpectedly
Anne Fajac   +14 more
doaj   +1 more source

Thermal Upsilon(1s) and chi_b1 suppression in sqrt(s_NN)=2.76 TeV Pb-Pb collisions at the LHC

open access: yes, 2011
I compute the thermal suppression of the Upsilon(1s) and chi_b1 states in sqrt(s_NN)=2.76 TeV Pb-Pb collisions. Using the suppression of each of these states I estimate the total R_AA for the Upsilon(1s) state as a function of centrality, rapidity, and ...
G. Aarts, Michael Strickland, T. Hatsuda
core   +1 more source

On Phase Noise Suppression in Full-Duplex Systems [PDF]

open access: yes, 2014
Oscillator phase noise has been shown to be one of the main performance limiting factors in full-duplex systems. In this paper, we consider the problem of self-interference cancellation with phase noise suppression in full-duplex systems. The feasibility
Ahmed, Elsayed, Eltawil, Ahmed M.
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

G6PD protects from oxidative damage and improves healthspan in mice

open access: yesNature Communications, 2016
The enzyme G6PD generates the reductive metabolite NADPH, which has antioxidant effects, but has also been linked to tumour growth. Here the authors generate mice that modestly overexpress G6PD and report increased lifespan in females, and no negative ...
Sandrina Nóbrega-Pereira   +7 more
doaj   +1 more source

Emotional Suppression and Oneiric Expression in Psychosomatic Disorders: Early Manifestations in Emerging Adulthood and Young Patients

open access: yesFrontiers in Psychology, 2019
BackgroundThe function of emotions, beginning from the proto-emotions, is the adaptation to the environment. This is based on the Homeorhesis, the equilibrium due to the adaptive operation of excitement and the dissipation of emotions.
Salvatore Settineri   +5 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Oncogenic and teratogenic effects of Trp53Y217C, an inflammation-prone mouse model of the human hotspot mutant TP53Y220C

open access: yeseLife
Missense ‘hotspot’ mutations localized in six p53 codons account for 20% of TP53 mutations in human cancers. Hotspot p53 mutants have lost the tumor suppressive functions of the wildtype protein, but whether and how they may gain additional functions ...
Sara Jaber   +13 more
doaj   +1 more source

A versatile drug delivery system targeting senescent cells

open access: yesEMBO Molecular Medicine, 2018
Senescent cells accumulate in multiple aging‐associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal β‐galactosidase activity of senescent cells to design a ...
Daniel Muñoz‐Espín   +18 more
doaj   +1 more source

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