Results 21 to 30 of about 1,138,079 (262)
Genetic suppression has provided a very powerful tool for analyzing C. elegans. Suppression experiments are facilitated by the ability to handle very large numbers of individuals and to apply powerful selections. Because the animal grows as a self-fertilizing diploid, both dominant and recessive suppressors can be recovered.
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AbstractGovernment agencies and large corporations meet similar problems related to control of agents dealing with outsiders: citizens under audit of the agency or clients of the company. In such interaction there typically exists a possibility of collusion.
Alexander Vasin +2 more
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Stabilization of p21 by mTORC1/4E-BP1 predicts clinical outcome of head and neck cancers
The molecular pathways involving p21 and mTORC1 are frequently deregulated in head and neck squamous cell carcinomas (HNSCC). Here, Llanos et al. report a mechanism that regulates p21 stability through the mTORC1/4E-BP1 pathway independently of p53, and ...
Susana Llanos +4 more
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Analysis of a Case of Supercellular Convection over Bulgaria: Observations and Numerical Simulations
A long-lived supercell developed in Northwest Bulgaria on 15 May 2018 and inflicted widespread damage along its track. The first part of this article presents a detailed overview of the observed storm evolution. Doppler radar observations reveal that the
Hristo G. Chipilski +5 more
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The Trp53 gene encodes several isoforms of elusive biological significance. Here, we show that mice lacking the Trp53 alternatively spliced (AS) exon, thereby expressing the canonical p53 protein but not isoforms with the AS C-terminus, have unexpectedly
Anne Fajac +14 more
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BackgroundThe function of emotions, beginning from the proto-emotions, is the adaptation to the environment. This is based on the Homeorhesis, the equilibrium due to the adaptive operation of excitement and the dissipation of emotions.
Salvatore Settineri +5 more
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Invited plenary talk presented on 4th International Conference on Physics and Astrophysics of Quark Gluon Plasma (ICPAQGP-2001), November 26-30, 2001, Jaipur; 12 pp, LaTeX, uses pramana ...
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Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
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G6PD protects from oxidative damage and improves healthspan in mice
The enzyme G6PD generates the reductive metabolite NADPH, which has antioxidant effects, but has also been linked to tumour growth. Here the authors generate mice that modestly overexpress G6PD and report increased lifespan in females, and no negative ...
Sandrina Nóbrega-Pereira +7 more
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