Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
Клиническая онкогематология, 2017 Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells.
Aleksandr Vasil’evich Ponomarev
doaj +1 more source
A study of the transmission characteristics of suppressor nozzles [PDF]
The internal noise radiation characteristics for a single stream 12 lobe 24 tube suppressor nozzle, and for a dual stream 36 chute suppressor nozzle were investigated.
Ahuja, K. K. +3 more
core +1 more source
Spontaneous phenotypic suppression of GacA-defective Vibrio fischeri is achieved via mutation of csrA and ihfA [PDF]
, 2015 Background: Symbiosis defective GacA-mutant derivatives of Vibrio fischeri are growth impaired thereby creating a selective advantage for growth-enhanced spontaneous suppressors. Suppressors were isolated and characterized for effects of the mutations on
Avitabile, Ashley +3 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
The reaction of cell factors of swine's organism immunobiological defense at mixed nematodosis
Российский паразитологический журнал, 2016 On pigs, experimentally infected by eggs Ascaris suum, Trichocephalus suis in a doze of respectively 500 and 200 eggs/kg of body weight, Oesophagostomum dentatum in a doze of 900 larva/kg and Strongyloides ransomi in a doze of 40 thousand of larva ...
S. I. Ponomar
doaj
Wind tunnel measurements of forward speed effects on jet noise from suppressor nozzles and comparison with flight test data [PDF]
The results of a test program conducted in the NASA Ames 40- by 80-Foot Wind Tunnel to determine the effect of forward speed on the noise levels emanating from a conical ejector nozzle, a 32-spoke suppressor nozzle, and a 104-elliptical-tube suppressor ...
Atencio, A., Jr.
core +1 more source
β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME [PDF]
, 2021 Hemn Mohammadpour +4 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Selective inhibitors of nuclear export for the treatment of non-Hodgkin’s lymphomas
Haematologica, 2013 The nuclear export protein chromosome maintenance region 1, found to be elevated in non-Hodgkin’s lymphomas, controls localization of critical tumor suppressor proteins.
Asfar S. Azmi +6 more
doaj +1 more source