Results 111 to 120 of about 817,665 (309)
Annals of Oncology, 1992 Genes responsible for the hereditary predisposition to a variety of human cancers have now been isolated. Their function seems to be part of complex signalling pathways involved in the control of cellular differentiation and the cell cycle. The presence of a single copy of these genes appears to be sufficient to ensure normal development, i.e. prevents
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Mechanical Engineering Journal, 2016 A vibration suppressor is used to change the natural frequency of an elevator rope, and to prevent resonance. The elevator rope is modeled using a string.
Hiroyuki KIMURA
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The reaction of cell factors of swine's organism immunobiological defense at mixed nematodosis
Российский паразитологический журнал, 2016 On pigs, experimentally infected by eggs Ascaris suum, Trichocephalus suis in a doze of respectively 500 and 200 eggs/kg of body weight, Oesophagostomum dentatum in a doze of 900 larva/kg and Strongyloides ransomi in a doze of 40 thousand of larva ...
S. I. Ponomar
doaj
A study of the transmission characteristics of suppressor nozzles [PDF]
The internal noise radiation characteristics for a single stream 12 lobe 24 tube suppressor nozzle, and for a dual stream 36 chute suppressor nozzle were investigated.
Ahuja, K. K. +3 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
Клиническая онкогематология, 2017 Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells.
Aleksandr Vasil’evich Ponomarev
doaj +1 more source
A theoretical approach to sound propagation and radiation for ducts with suppressors [PDF]
The several phenomena involved in theoretical prediction of the far-field sound radiation attenuation from an acoustically lined duct were studied. These include absorption by the suppressor, termination reflections, and far-field radiation.
Rice, E. J., Sawdy, D. T.
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source