Results 111 to 120 of about 880,593 (358)

A theoretical approach to sound propagation and radiation for ducts with suppressors [PDF]

The several phenomena involved in theoretical prediction of the far-field sound radiation attenuation from an acoustically lined duct were studied. These include absorption by the suppressor, termination reflections, and far-field radiation.
Rice, E. J., Sawdy, D. T.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

SMARCB1/INI1 Tumor Suppressor Gene Is Frequently Inactivated in Epithelioid Sarcomas [PDF]

, 2005
Piergiorgio Modena, Elena Lualdi, Federica Facchinetti, Lisa Galli, Manuel R. Teixeira, Silvana Pilotti, Gabriella Sozzi   +6 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Identification of RNA silencing suppressor encoded by citrus chlorotic dwarf-associated virus

Frontiers in Microbiology
IntroductionCitrus chlorotic dwarf-associated virus (CCDaV) is an economically important citrus virus associated with leaf curling, deformation, and chlorosis found in China.
Xiao Ye, Dongdong Ding, Yuan Chen, Chuang Liu, Zhongan Li, Binghai Lou, Yan Zhou   +6 more
doaj   +1 more source

Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma [PDF]

, 2016
Niels Weinhold, Cody Ashby, Leo Rasche, Shweta S. Chavan, Joshua Epstein, Owen Stephens, Ruslana G. Tytarenko, Michael Bauer, Tobias Meißner, Shayu Deshpande, Purvi H. Patel, Tímea Buzder, Gábor Molnár, Erich A. Peterson, Frits van Rhee, Maurizio Zangari, Sharmilan Thanendrarajan, Carolina Schinke, Erming Tian, Joshua Epstein, Bart Barlogie, Faith E. Davies, Christoph Heuck, Brian A. Walker, Gareth J. Morgan   +24 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The Heterologous Expression of the p22 RNA Silencing Suppressor of the Crinivirus Tomato Chlorosis Virus from Tobacco Rattle Virus and Potato Virus X Enhances Disease Severity but Does Not Complement Suppressor-Defective Mutant Viruses

Viruses, 2017
To counteract host antiviral RNA silencing, plant viruses express suppressor proteins that function as pathogenicity enhancers. The genome of the Tomato chlorosis virus (ToCV) (genus Crinivirus, family Closteroviridae) encodes an RNA silencing suppressor,
Yazmín Landeo-Ríos, Jesús Navas-Castillo, Enrique Moriones, M. Carmen Cañizares   +3 more
doaj   +1 more source

Signal Pathway of Hypoxia-Inducible Factor-1α Phosphorylation and its Interaction with von Hippel-Lindau Tumor Suppressor Protein During Ischemia in MiaPaCa-2 Pancreatic Cancer Cells [PDF]

, 2005
Seok‐Joon Kwon, Jae J. Song, Yong J. Lee   +2 more
openalex   +1 more source

Transcriptional repression of Myc underlies AGO1’s tumour suppressor function [PDF]

, 2020
Olga Zaytseva, Naomi Mitchell, Linna Guo, Owen J. Marshall, Linda M. Parsons, Ross D. Hannan, David Levens, Leonie M. Quinn   +7 more
openalex   +1 more source