Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley +1 more source
Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando +10 more
wiley +2 more sources
Nanographenic bowls based on contorted hexabenzocoronene: Synthesis, structure, and supramolecular assembly with fullerene C<sub>60</sub>. [PDF]
Sun Y +12 more
europepmc +1 more source
Bacterial immune activation via supramolecular assembly with phage triggers. [PDF]
Zhang T +6 more
europepmc +1 more source
Non‐Dilute Synthesis of Macrodiolides and Macrotetrolides Enabled by Confinement Catalysis
Confinement catalysis within a hexameric resorcin[4]arene capsule enables macrolactonization under non‐dilute conditions (up to 0.1 M), overcoming the limitations of high‐dilution protocols (0.1–10 mM). This strategy provides direct access to 18–32‐membered macrodiolides and 26–32‐membered macrotetrolides in one pot and unlocks previously inaccessible ...
Feng‐Yuan Wang +3 more
wiley +2 more sources
Chiral supramolecular assembly to enhance the magneto-optical rotation of organic materials. [PDF]
Delage-Laurin L +11 more
europepmc +1 more source
Redirecting Excited‐State Proton Transfer Through Supramolecular Polymerization in Nanoconfinement
Supramolecular confinement redirects the excited‐state proton transfer pathway of an amphoteric emitter. In water, the molecule undergoes ESPD, whereas co‐assembly with γ‐cyclodextrin forms nanotubes that template slip‐stacked emitter pairs and enable ESIMPT. Structural and photophysical characterization of the assemblies shows that the preorganization
Luis C. Pantaleone +8 more
wiley +2 more sources
Synthesis, Supramolecular Assembly, and Hydrogelation of Poly(amino ester) ABA Triblock Copolymers. [PDF]
Pascouau C +6 more
europepmc +1 more source
Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition
Non‐covalent co‐assembly of BTA with antiviral surfactants produces ratio‐dependent morphologies. Fibrous supramolecular polymers exhibit superior HSV‐1 inhibition, revealing multivalent fiber‐virus interactions and highlighting supramolecular co‐assemblies as a powerful strategy for functional biomedical nanomaterials with demonstrated tunable ...
Christian Zoister +12 more
wiley +2 more sources
Unveiling the supramolecular assembly of a novel antimony(iii)-based co-crystal: integrating multi-spectroscopic analyses, DFT calculations, and advanced biological evaluations. [PDF]
Elleuch N +5 more
europepmc +1 more source

