Results 151 to 160 of about 59,477 (294)

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

open access: yesAdvanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller   +6 more
wiley   +1 more source

Triptycene-like naphthopleiadene as a readily accessible scaffold for supramolecular and materials chemistry

open access: yes
Triptycene derivatives are used extensively in supramolecular and materials chemistry, however, most are prepared using multi-step synthesis involving the generation of a benzyne intermediate, which hinders production on a large scale.
Shuhua, Pang   +5 more
core   +1 more source

Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces

open access: yesAdvanced Science, EarlyView.
Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein   +6 more
wiley   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

Red OLED with efficiency of 25.6% at 10,000 cd m−2 based on selenium embedding multiple resonance framework

open access: yesLight: Science & Applications
Multiple resonance thermally activated delayed fluorescence (MR-TADF) materials featuring narrowband emission and high luminescence efficiency hold great promise for ultra-high-definition displays.
Yexuan Pu   +5 more
doaj   +1 more source

Molecular Self-Assembly and Supramolecular Chemistry of Cyclic Peptides. [PDF]

open access: yesChem Rev, 2021
Song Q   +6 more
europepmc   +1 more source

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