Results 11 to 20 of about 1,102 (170)

Supramolecular Frameworks Based on Rhenium Clusters Using the Synthons Approach [PDF]

Molecules, 2021
The reaction of the K4[{Re6Si8}(OH)a6]·8H2O rhenium cluster salt with pyrazine (Pz) in aqueous solutions of alkaline or alkaline earth salts at 4 °C or at room temperature leads to apical ligand exchange and to the formation of five new compounds: [trans-
Nathalie Audebrand, Antoine Demont, Racha El Osta, Yuri V. Mironov, Nikolay G. Naumov, Stéphane Cordier   +5 more
doaj   +4 more sources

Supramolecular Synthons in Protein-Ligand Frameworks. [PDF]

Cryst Growth Des
Supramolecular synthons, defined as reproducible intermolecular structural units, have greatly aided small molecule crystal engineering. In this paper, we propose that supramolecular synthons guide ligand-mediated protein crystallization. The protein RSL and the macrocycle sulfonato-calix[8]arene cocrystallize in at least four ways.
Flood RJ, Mockler NM, Thureau A, Malinska M, Crowley PB.   +4 more
europepmc   +3 more sources

Modular protein frameworks via supramolecular synthons. [PDF]

Biophys Rev
Abstract Controlled protein assembly and protein crystal engineering are routes to new types of biomaterials. In this review, we examine how crystal engineering concepts, including polymorph searching, molecular tectonics and supramolecular synthons, can be adapted and applied in protein-based systems.
Mockler NM, Crowley PB.
europepmc   +3 more sources

Making and Breaking Supramolecular Synthons for Modular Protein Frameworks. [PDF]

Chemistry
AbstractAnionic calixarenes are useful mediators of protein assembly. In some cases, protein – calixarene cocrystallization yields multiple polymorphs. Ralstonia solanacearum lectin (RSL) cocrystallizes with p‐sulfonato‐calix[8]arene (sclx8) in at least four distinct pH‐dependent arrangements.
Mockler NM, Raston CL, Crowley PB.
europepmc   +3 more sources

Supramolecular Synthons: Will Giant Rigid Superspheres Do? [PDF]

Cryst Growth Des, 2016
For the first time, the concept of supramolecular synthons was applied to giant rigid superspheres based on pentaphosphaferrocene [CpRFe(η5-P5)] (R = Me, Et) and Cu(I) halides, which reach 2.1-3.0 nm in diameter. Two supramolecular synthons, σ-π and π-π, are discovered based on halogen···CpR and Cp*···Cp* specific interactions, respectively.
Peresypkina E, Virovets A, Scheer M.
europepmc   +4 more sources

Intermolecular Hydrogen Bonding in Alpha-Hydroxy Carboxylic Acids Crystals: Connectivity, Synthons, Supramolecular Motifs

Crystals, 2022
Synthon theory underlies the analysis and empirical prediction of the crystal structure. Supramolecular synthons (SMSs) formed by intermolecular hydrogen bonds, such as carboxylic R22(8) and C11(4) and alcoholic C11(2) ones, are among the most popular ...
Alexander A. Bredikhin, Robert R. Fayzullin, Aidar T. Gubaidullin, Zemfira A. Bredikhina   +3 more
doaj   +1 more source

Chiral Triptycenes in Supramolecular and Materials Chemistry

ChemistryOpen, 2020
Triptycenes are an intriguing class of organic molecules with several unusual characteristics, such as a propeller‐like shape, saddle‐like cavities around a symmetrical scaffold, a rigid π‐framework. They have been extensively studied and proposed as key
Giovanni Preda, Dr. Andrea Nitti, Prof. Dario Pasini   +2 more
doaj   +1 more source

Rational Coformer Selection in the Development of 6-Propyl-2-thiouracil Pharmaceutical Cocrystals

Pharmaceuticals, 2023
Pharmaceutical multicomponent solids have proved to efficiently modulate the physicochemical properties of active pharmaceutical ingredients. In this context, polyphenols are interesting coformers for designing pharmaceutical cocrystals due to their wide
Francisco Javier Acebedo-Martínez, Carolina Alarcón-Payer, Cristóbal Verdugo-Escamilla, Jesús Martín, Antonio Frontera, Alicia Domínguez-Martín, Jaime Gómez-Morales, Duane Choquesillo-Lazarte   +7 more
doaj   +1 more source

Cocrystal of 4-Nitrophenol and 2,1,3-Benzoselenadizole

Molbank, 2023
The 1:1 cocrystal of 4-nitrophenol (NP) and 2,1,3-benzoselenadiazole (BSA) was successfully synthesized. The X-ray single-crystal diffraction analysis revealed that the structure contained a [Se–N]2 cyclic supramolecular synthon.
Honghong Lan, Shaobin Miao, Weizhou Wang
doaj   +1 more source

Supramolecular synthon hierarchy in sulfonamide cocrystals with syn-amides and N-oxides

IUCrJ, 2019
Sulfonamide drugs are well known antibacterial and antimicrobial molecules for pharmaceutical development. Building a library of suitable supramolecular synthons for the sulfonamide functional group and understanding their crystal structures with partner
Geetha Bolla, Ashwini Nangia
doaj   +1 more source