Results 51 to 60 of about 44,405 (256)

Environmental Risk Factors for Progressive Supranuclear Palsy [PDF]

Journal of Movement Disorders, 2021
Typically, progressive supranuclear palsy (PSP) is clinically characterized by slow vertical saccades or supranuclear gaze palsy, levodopa-resistant parkinsonism with predominant axial symptoms, and cognitive executive impairment.
Hee Kyung Park, Sindana D. Ilango, Irene Litvan   +2 more
doaj   +1 more source

Zolpidem in Progressive Supranuclear Palsy

Case Reports in Neurological Medicine, 2013
Progressive supranuclear palsy (PSP) is a progressive neurodegenerative disorder, characterized by motor symptoms, postural instability, personality changes, and cognitive impairment. There is no effective treatment for this disorder.
Sandip K. Dash
doaj   +1 more source

Elevated Levels of Methylmalonate and Homocysteine in Parkinson's Disease, Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis [PDF]

, 2010
Background/Aims: Increasing evidence suggests that elevated levels of homocysteine (Hcy) and methylmalonate (MMA) may be involved in the pathogenesis of neurodegenerative diseases. Methods: The urine levels of MMA and serum levels of Hcy as well as folic
Bötzel, Kai, Giese, Armin, Levin, Johannes, Lorenzl, Stefan, Vogeser, Michael   +4 more
core   +1 more source

Criteria for the diagnosis of corticobasal degeneration [PDF]

, 2013
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations.
Armstrong, Melissa J, Bak, Thomas H, Bhatia, Kailash P, Borroni, Barbara, Boxer, Adam L, Dickson, Dennis W, Grossman, Murray, Hallett, Mark, Josephs, Keith A, Kertesz, Andrew, Lang, Anthony E, Lee, Suzee E, Litvan, Irene, Miller, Bruce L, Reich, Stephen G, Riley, David E, Tolosa, Eduardo, Tröster, Alexander I, Vidailhet, Marie, Weiner, William J   +19 more
core   +1 more source

Procerus sign: Mechanism, clinical usefulness, and controversies

Annals of Indian Academy of Neurology, 2018
This sign is observed in atypical parkinsonism mainly in Progressive Supranuclear Palsy. The exact mechanism of this sign is not clear but the contraction of the Corrugator Supercilii muscle is the most important factor for the generation of vertical ...
Shakya Bhattacharjee
doaj   +1 more source

Corticobasal syndrome: neuroimaging and neurophysiological advances [PDF]

, 2019
Corticobasal degeneration (CBD) is a neurodegenerative condition characterized by 4R-tau protein deposition in several brain regions that clinically manifests itself as a heterogeneous atypical parkinsonism typically expressing in the adulthood.
Asci, Francesco, Berardelli, Alfredo, Bologna, Matteo, Colosimo, Carlo, Di Stasio, Flavio, Fabbrini, Giovanni, Marsili, Luca, Pantano, Patrizia, Suppa, Antonio, Upadhyay, Neeraj   +9 more
core   +1 more source

Variation at the TRIM11 Locus Modifies Progressive Supranuclear Palsy Phenotype [PDF]

, 2018
Objective The basis for clinical variation related to underlying progressive supranuclear palsy (PSP) pathology is unknown. We performed a genome‐wide association study (GWAS) to identify genetic determinants of PSP phenotype.
Armstrong, Blauwendraat, Chang, Chen, Coetzee, Daniel, Galvin, Giambartolomei, Gong, Hassan, Hatakeyama, Hawrylycz, Hoglinger, Hoglinger, Hughes, Kontaxi, Lambert, Lassot, Leeuw, Ling, Litvan, Magiera, Maston, Morris, Murthy, Myeku, Nath, Ramasamy, Reed, Respondek, Sanders, Schrag, Steele, Takahashi, Williams, Williams, Williams, Ying, Young, Zhang   +39 more
core   +3 more sources

Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. [PDF]

, 2014
We report the case of a 75-year-old ex-professional boxer who developed diplopia and eye movement abnormalities in his 60's followed by memory impairment, low mood and recurrent falls.
Hardy, J, Holton, JL, Houlden, H, Kara, E, Lees, AJ, Ling, H, Martino, D, Plant, GT, Revesz, T   +8 more
core   +2 more sources

Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome

JAMA Neurology, 2019
This cohort study defines the distinguishing features of progressive supranuclear palsy and corticobasal syndrome and assesses their usefulness in facilitating early diagnosis and separation from Parkinson disease among patients with atypical ...
E. Jabbari, N. Holland, V. Chelban, P. S. Jones, R. Lamb, Charlotte V Rawlinson, Tong Guo, Alyssa A Costantini, Manuela M. X. Tan, A. Heslegrave, F. Roncaroli, J. Klein, O. Ansorge, Kieren Allinson, Z. Jaunmuktane, J. Holton, T. Révész, T. T. Warner, Andrew J Lees, H. Zetterberg, L. Russell, M. Bocchetta, J. Rohrer, Nigel M Williams, D. Grosset, David J. Burn, N. Pavese, A. Gerhard, C. Kobylecki, P. N. Leigh, A. Church, M. Hu, J. Woodside, H. Houlden, J. Rowe, H. Morris   +35 more
semanticscholar   +1 more source

REM sleep behavior in Parkinson disease: Frequent, particularly with higher age.

PLoS ONE, 2020
This retrospective single-center polysomnography-based study was designed to assess the frequency of REM sleep behavior disorder (RBD) in consecutive patients with Parkinsonism, including Parkinson disease, dementia with Lewy bodies, multiple system ...
Heide Baumann-Vogel, Hyun Hor, Rositsa Poryazova, Philipp Valko, Esther Werth, Christian R Baumann   +5 more
doaj   +1 more source