Results 81 to 90 of about 44,405 (256)

Clinical features of supranuclear palsy

Бюллетень сибирской медицины, 2009
Progressive supranuclear palsy related to neurodegenerative diseases of the brain. In the pathological process involved, and stem structure. The disease manifests a combination of progressive akinetic-rigid syndrome and early development of postural ...
T. A. Valikova, V. M. Alifirova, N. V. Pugachenko, R. B. Tsyrenzhapova, A. B. Bichik   +4 more
doaj   +1 more source

Progressive Supranuclear Palsy [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1987
ABSTRACT:Progressive supranuclear palsy (PSP) was first recognized as a distinct morbid entity by Richardson, Steele and Olszewski a quarter century ago. Subsequent experience has confirmed and extended their original observations. PSP has become familiar as a chronic progressive disorder with extrapyramidal rigidity, bradykinesia, gait impairment ...
Joseph Jankovic, Haydee Rohaidy
openaire   +1 more source

Neuroinflammation and Tau Colocalize in vivo in Progressive Supranuclear Palsy

Annals of Neurology, 2020
We examined the relationship between tau pathology and neuroinflammation using [11C]PK11195 and [18F]AV‐1451 PET in 17 patients with progressive supranuclear palsy (PSP) Richardson's syndrome.
M. Malpetti, L. Passamonti, T. Rittman, P. Jones, Patricia Vázquez Rodríguez, W. R. Bevan-Jones, Young T. Hong, T. Fryer, F. Aigbirhio, J. O'Brien, J. Rowe   +10 more
semanticscholar   +1 more source

Genetics of Progressive Supranuclear Palsy: A Review

Journal of Parkinson's Disease, 2020
Progressive supranuclear palsy (PSP) is an atypical parkinsonism with prominent 4R-tau neuropathology, and the classical clinical phenotype is characterized by vertical supranuclear gaze palsy, unprovoked falls, akinetic-rigid syndrome and cognitive ...
Yafei Wen, Yafang Zhou, Bin Jiao, Lu Shen   +3 more
semanticscholar   +1 more source

Serious Illness Conversation in the Care of Atypical Parkinsonian Disorders: A Practical Guide for Neurology Clinicians

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Compared to Parkinson's disease, atypical parkinsonian disorders (APD) are characterized by a more rapidly progressive course, often leading to profound disability. Effective communication between clinicians, patients, and care partners is essential to support patient‐centered care and shared decision‐making.
Michiko K. Bruno, Jocelyn Jiao, Neha M. Kramer, Margaret Ivancic, Claudia Chou, Jessica Shurer, Thomas Carroll, on behalf of CurePSP Centers of Care Palliative Care Working Group   +7 more
wiley   +1 more source

Progressive supranuclear palsy: A case report and brief review of the literature

Radiology Case Reports
Atypical Parkinsonian syndromes are a subset of progressive neurodegenerative disorders that present with signs of Parkinson's disease. However, due to multisystem degeneration, the atypical Parkinsonian syndromes have additional symptoms that are often ...
Vivek Batheja, MD, Morgan Fish, DO, Aneri B. Balar, MD, Jeffery P. Hogg, MD, FACR, Dhairya A. Lakhani, MD, Musharaf Khan, DO   +5 more
doaj   +1 more source

Affective symptoms in progressive supranuclear palsy

Journal of Geriatric Mental Health, 2014
Progressive supranuclear palsy is an unusual neurodegenerative disorder, which superficially resembles Parkinson′s disease, and the initial manifestations are characterized by depression, akinesia and mild cognitive impairment.
K S Shaji, K S Jyothi
doaj   +1 more source

Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials [PDF]

, 2016
INTRODUCTION: Clinical and MRI measurements can track disease progression in PSP, but many have not been extensively evaluated in multicenter clinical trials.
AL-108-231 Investigators, ., Bang, J, Boxer, AL, Doody, RS, Gold, M, Grossman, M, Knopman, DS, Lang, AE, Lees, A, Lobach, IV, Miller, BL, Morimoto, BH, Schneider, LS   +12 more
core   +1 more source

Automated MRI Classification in Progressive Supranuclear Palsy: A Large International Cohort Study

Movement Disorders, 2020
The Magnetic Resonance Parkinsonism Index is listed as one of the most reliable imaging morphometric markers for diagnosis of progressive supranuclear palsy (PSP).
Salvatore Nigro, A. Antonini, D. Vaillancourt, K. Seppi, R. Ceravolo, A. Strafella, A. Augimeri, A. Quattrone, M. Morelli, Luca Weis, E. Fiorenzato, R. Biundo, Roxana G. Burciu, F. Krismer, Nikolaus R. McFarland, Christoph Mueller, E. Gizewski, M. Cosottini, E. Del Prete, S. Mazzucchi, A. Quattrone   +20 more
semanticscholar   +1 more source

Comparative Analysis of the Incidence, Prevalence, and Survival of 8 Types of Parkinsonism in a Population‐Based Study with 367 Million Person Years of Observation over 21 Years

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi, Katherine A. Grosset, Prasanth A. Iruthayaraj, Romel Gravesande, Lance Lee, Cathal Doyle, Yoav Ben‐Shlomo, Donald G. Grosset   +7 more
wiley   +1 more source