Results 71 to 80 of about 49,084 (266)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

La formación de educadores infantiles en cuatro países de Sur América

, 2018
El presente proyecto de investigación se realiza con el fin de conocer las perspectivas de formación en el campo de la educación infantil en cuatro países de Sur América, y desde allí establecer un análisis comparativo entre dichos países y la ...
Rabitz Ortegón, Mónica, Carreño Torres, Karol Stefania, González Marín, Laura Alejandra, Méndez Martínez, Giovanna Constanza   +3 more
core  

THE MANAGEMENT OF VISIBLE AND INVISIBLE DIVERSITY IN ORGANIZATIONS

Visión de Futuro
The objectives of this article are to review the literature of Sixty-three (63) documents on the management of visible and invisible diversity in organizations, for which a tour of the background is carried out, the concept of diversity; the legitimacy ...
Manuel Alfonso Garzón Castrillon
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Operación Cóndor: antecedentes teóricos y consideraciones estratégicas

Relaciones Internacionales, 2018
Para la generación de sudamericanos que nacimos en la década de los setenta nos es muchas veces difícil comprender por qué nuestros países pudieron llegar a tener gobiernos autoritarios de la talla de Augusto Pinochet y de Jorge Rafael Videla.
Linda M. Palumbo Olszanski
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

LA GESTIÓN DE LA DIVERSIDAD VISIBLE E INVISIBLE EN LAS ORGANIZACIONES

Visión de Futuro
Los objetivos de este artículo son revisar la literatura de sesenta y tres (63) documentos sobre, la gestión de la diversidad visible e invisible en las organizaciones, para lo cual se realiza un recorrido por los antecedentes, el concepto de diversidad;
Manuel Alfonso Garzón Castrillon
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Plan de importación de sistemas hidráulicos para bombeo de agua, fabricados en Centro y Sur América.

, 2016
La relación más importante entre los países está sustentada en el comercio internacional, por lo que su actividad origina una fuerza de desarrollo económico; las importaciones permiten a los inversionistas y empresas adquirir productos que en su país no ...
Palacios Trejo, Karen Sthefanie, Ortega de Alvarenga, Dalia Estela, Guardado García, Jeny del Carmen   +2 more
core