Results 91 to 100 of about 55,425 (314)
Litigio Climático y Derechos Humanos en el Sur Global. Apuntes para el debate
El presente artículo aborda la creciente práctica del litigio climático como herramienta vital para enfrentar la crisis climática global, especialmente enfocada en la justicia climática y la intersección con los derechos humanos. A pesar de los esfuerzos
Juan Auz Vaca
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Feminismes enfront de la guerra contra les dones del Sud global
Carlos Zeller Orellana
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La Cooperación Sur-Sur y el desarrollo del Sur global
South-South Cooperation (SSC) has seen a significant increase in volume and importance, especially since 2008. In this context, the aim of this thesis is to examine whether or not Southern providers of SSC are promoting favorable conditions for the sustainability of Global South development through their cooperation, focusing on three relevant areas ...
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Innovación frugal: un análisis bibliométrico de la evolución de un nuevo campo de conocimiento
La innovación frugal se centra en el desarrollo de productos y servicios accesibles, a partir de materiales reutilizables, reciclables, reparables y de bajo costo.
Paula Elisabeth García Farfán +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Género; Colonialidad; Política pública; Salud; Sur global
RESUMEN: Se propone un análisis de políticas públicas que articulan género y salud en América Latina, para repensar la dimensión global de la construcción de conceptos, indicadores e instrumentos de evaluación de impactos de estas políticas en la región.
López, Laura Cecilia +2 more
openaire +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
El acaparamiento de tierras (land grabbing) refiere al proceso de adquisiciones a gran escala de tierras agrícolas en otros estados, desatado en el contexto de la convergencia de crisis internacionales —alimentaria, energética, financiera y climática— de
Sol Yamila MORA
doaj

