The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Thermal Analysis and Hybrid Compensation Design of a 10× Optical Zoom Periscope Lens for Smartphones. [PDF]
Liu YH, Tien CL, Su YL, Sun WS, Hsu YS.
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Asymmetric design of a Pt/C catalyst layer for enhanced performance in proton exchange membrane fuel cells. [PDF]
Li J +7 more
europepmc +1 more source
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Reconceptualizing Peri-Implantitis: Dual-Factor Inflammation and Its Role in Advancing Biomaterial Coatings. [PDF]
Cunha DM +6 more
europepmc +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
New Strategy Based on Click Reaction for Preparation of 3-Acyl-4-hydroxycoumarin-Modified Silica as a Perspective Material for the Separation of Rare Earth Elements. [PDF]
Konshina DN +4 more
europepmc +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
Mechanism of Long-Term Corrosion Protection for Silicone Epoxy Coatings Reinforced by BN-PDA-CeO2 Ternary Composites in Harsh Environments. [PDF]
Mu X, Jin T, Xie P, Yu R, Li B, Yuan X.
europepmc +1 more source

