Results 51 to 60 of about 731,643 (313)
The surface of metal mirrors is often polished by electroless coating with a Ni–P modified layer after single-point diamond turning. In practice, however, improvements in mirror quality are closely related to the polishing environment, polishing medium ...
Hao Hu +7 more
doaj +1 more source
Influence of higher order effects on the vortex instability of thermal boundary layer flow in a wedge shaped domain [PDF]
We reconsider the onset of streamwise vortices in the thermal boundary layer flow induced by an inclined upward-facing heated semi-infinite surface placed within a Newtonian fluid.
Rees, DAS +5 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Nonlinear disturbance evolution in a two-dimensional boundary layer along an elastic plate and induced radiated sound [PDF]
The interaction between a boundary-layer flow and an elastic plate is addressed by direct numerical simulation, taking into account the full coupling between the fluid flow and the flexible wall.
EHRENSTEIN, Uwe +5 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Pulsed detonation–plasma technology (PDT) is a surface-modification technology used in an atmospheric environment, where plasma, a detonation impact and thermal conditions are combined and have an effect on the material’s surface. In this study, annealed
Youxing He +4 more
doaj +1 more source
Introduction: Nanomaterials aggregation within polyamide (PA) layer of thin film nanocomposite (TFN) membrane is found to be a common issue and can negatively affect membrane filtration performance.
Ying Siew Khoo +5 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

