Results 61 to 70 of about 1,307,233 (284)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Unusual synchronization phenomena during electrodissolution of silicon: the role of nonlinear global coupling

, 2014
The photoelectrodissolution of n-type silicon constitutes a convenient model system to study the nonlinear dynamics of oscillatory media. On the silicon surface, a silicon oxide layer forms.
García-Morales, Vladimir, Krischer, Katharina, Schmidt, Lennart, Schönleber, Konrad   +3 more
core   +1 more source

pH responsive biomineralization onto chitosan grafted biodegradable substrates [PDF]

, 2008
Bioactive composites that enable the formation of an apatite layer onto the surface are important in the development of osteoconductive biomaterials in orthopaedic applications.
Alves, N. M., Dias, Catarina I., Mano, J. F.   +2 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Modification mechanism of Cu–Al alloy with pre-cladded Al/AlY layers treated by plasma nitriding: Experiments and first-principles calculations

Journal of Materials Research and Technology
The improvement in the properties of aluminum bronze alloys after nitriding is limited due to the immiscibility of nitrogen atoms with the copper matrix. To address this issue, a Cu-Al intermetallic compound prelayer is used, and the rare earth element Y
Xiaoxian Li, Lingling Liu, Xiang Wang, Xuehui Zhang, Tongxiang Liang   +4 more
doaj   +1 more source

A simple model for the short-time evolution of near-surface current and temperature profiles [PDF]

, 2004
A simple analytical/numerical model has been developed for computing the evolution, over periods of up to a few hours, of the current and temperature profile in the upper layer of the ocean. The model is based upon conservation laws for heat and momentum,
Jenkins, Alastair D., Ward, Brian
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adhesion of endothelial cells and adsorption of serum proteins on gas plasma-treated polytetrafluoroethylene [PDF]

, 1991
From in vitro experiments it is known that human endothelial cells show poor adhesion to hydrophobic polymers. The hydrophobicity of vascular prostheses manufactured from Teflon® or Dacron® may be the reason why endothelialization of these grafts does ...
Aken, W.G. van, Bantjes, A., Beugeling, T., Dekker, A., Feijen, J., Reitsma, K.   +5 more
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source